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Cat. No.: HY-P81915A

Integrin alpha 9 Antibody (YA1660)(PBS only)

Name: Integrin alpha 9 Antibody (YA1660)(PBS only)
Brand: MedChemExpress
SKU: HY-P81915A
Availability: PreOrder

(Synonyms: Alpha RLC; ITGA4L; ITGA9; RLC)

Integrin alpha 9 Antibody (YA1660) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Integrin alpha 9.

For research use only. We do not sell to patients.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio	1:1000-1:5000	1:100-1:200

Description

Integrin alpha 9 Antibody (YA1660) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Integrin alpha 9.

Host Rabbit
Species Reactivity
Human, Mouse, Rat
Observed Molecular Weight

Observed band size: 140 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 114 kDa

Immunogen

A synthesized peptide derived from human Integrin alpha 9

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

Integrin alpha 9 is an Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. ITGA9:ITGB1 may play a crucial role in SVEP1/polydom-mediated myoblast cell adhesion. Integrin ITGA9:ITGB1 represses PRKCA-mediated L-type voltage-gated channel Ca(2+) influx and ROCK-mediated calcium sensitivity in vascular smooth muscle cells via its interaction with SVEP1, thereby inhibiting vasocontraction^[1].
Subcellular Localization

Membrane; Single-pass type I membrane protein
Expression

Tissue_specificity:Expressed in vascular smooth muscle cells (at protein level) (PubMed:35802072) . Expressed in the airway epithelium (at protein level) (PubMed:8245132)
Subunit

Heterodimer of an alpha and a beta subunit. Alpha-9 (ITGA9) associates with beta-1 (ITGB1). Integrin ITGA9:ITGB1 interacts with FBLN5 (via N-terminus).
SwissProt ID

Q13797
Gene ID

3680 [NCBI]
Synonyms

Alpha RLC; ITGA4L; ITGA9; RLC
Research Field

Signal Transduction