Integrin alpha 9 Antibody (YA1660)(PBS only)

Cat. No.: HY-P81915A: Data Sheet User Guide for Antibodies
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Integrin alpha 9 Antibody (YA1660) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Integrin alpha 9.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Integrin alpha 9 Antibody (YA1660) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Integrin alpha 9.

Host

Rabbit

Molecular Weight

Predicted band size: 114 kDa;

Observed band size: 140 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q13797

Gene ID

3680 [NCBI]

Immunogen

A synthesized peptide derived from human Integrin alpha 9

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200

Purity	Affinity Chromatography	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. ITGA9:ITGB1 may play a crucial role in SVEP1/polydom-mediated myoblast cell adhesion (By similarity). Integrin ITGA9:ITGB1 represses PRKCA-mediated L-type voltage-gated channel Ca(2+) influx and ROCK-mediated calcium sensitivity in vascular smooth muscle cells via its interaction with SVEP1, thereby inhibiting vasocontraction (PubMed:35802072)

Subcellular Localization：Membrane; Single-pass type I membrane protein

Expression：
Tissue_specificity:Expressed in vascular smooth muscle cells (at protein level) (PubMed:35802072) . Expressed in the airway epithelium (at protein level) (PubMed:8245132)

Subunit：Heterodimer of an alpha and a beta subunit. Alpha-9 (ITGA9) associates with beta-1 (ITGB1). Integrin ITGA9:ITGB1 interacts with FBLN5 (via N-terminus).

Research Field

Signal Transduction

Synonyms

Alpha RLC; ITGA4L; ITGA9; RLC

Documentation

User Guide for Antibodies (1077 KB)