KCTD13 Antibody (YA8754)
(Synonyms: BACURD1; FKSG86; hBACURD1; PDIP1; POLDIP1)KCTD13 Antibody (YA8754) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KCTD13.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
KCTD13 Antibody (YA8754) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KCTD13.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 36.2 kDa
Full length human recombinant protein of human KCTD13 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KCTD13 is a Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission. The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission[1].
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Expressed in a wide variety of tissues
Induction: By TNF and IL6/interleukin-6 -
Isoforms & Post-Translational Modification
Q8WZ19: 329 amino acids, molecular weight 36357 Da.
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Subunit
Homotetramer; forms a two-fold symmetric tetramer in solution (PubMed:28963344)
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SwissProt ID
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Synonyms
BACURD1; FKSG86; hBACURD1; PDIP1; POLDIP1
Documentation
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