KDELC2 Antibody (YA8775)
(Synonyms: MGC33424)KDELC2 Antibody (YA8775) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KDELC2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:150-500 |
Product Details
KDELC2 Antibody (YA8775) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KDELC2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 58.4 kDa
Full length human recombinant protein of human KDELC2 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KDELC2 is a Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently. Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1. May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway[1][2].
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Subcellular Localization
Endoplasmic reticulum lumen
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Isoforms & Post-Translational Modification
Q7Z4H8 has three isomers: Q7Z4H8-1: 58572 Da (predicted); Q7Z4H8-2: 52708 Da (predicted); Q7Z4H8-3: 47400 Da (predicted).
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SwissProt ID
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Synonyms
MGC33424
Documentation
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