KLC2 Antibody (YA8363)
(Synonyms: SPOAN)KLC2 Antibody (YA8363) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KLC2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:2000-2500 |
Product Details
KLC2 Antibody (YA8363) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KLC2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
Human recombinant protein fragment corresponding to amino acids 335-622 of human KLC2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Envío
Shipping with blue ice.
Background
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Function
KLC2 is a Kinesin is a microtubule-associated force-producing protein that plays a role in organelle transport. The light chain functions in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (Probable). Through binding with PLEKHM2 and ARL8B, recruits kinesin-1 to lysosomes and hence direct lysosomes movement toward microtubule plus ends[1].
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Subcellular Localization
Cytoplasm, cytoskeleton,Lysosome membrane
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Isoforms & Post-Translational Modification
Q9H0B6 has two isomers: Q9H0B6-1: 68935 Da (predicted); Q9H0B6-2: 60047 Da (predicted).
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Subunit
Oligomeric complex composed of two heavy chains and two light chains (Probable)
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SwissProt ID
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Synonyms
SPOAN
Documentación
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