KLF11 Antibody (YA8089)
(Synonyms: FKLF; FKLF1; MODY7; TIEG2; Tieg3)KLF11 Antibody (YA8089) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KLF11.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:800-1500 |
Product Details
KLF11 Antibody (YA8089) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KLF11.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 55 kDa
Human recombinant protein fragment corresponding to amino acids 1-274 of human KLF11 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KLF11 transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis[1][2][3].
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Ubiquitous. Higher expression in erythroid cells
Induction: By TGFB1 -
Isoforms & Post-Translational Modification
O14901 has two isomers: O14901-1: 55139 Da (predicted); O14901-2: 53329 Da (predicted).
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Subunit
Interacts with SIN3A
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SwissProt ID
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Synonyms
FKLF; FKLF1; MODY7; TIEG2; Tieg3
Documentation
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