KLF11 Antibody (YA8089)

製品番号: HY-P88405: データシート User Guide for Antibodies
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KLF11 Antibody (YA8089) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KLF11.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

KLF11 Antibody (YA8089) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KLF11.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 55 kDa

Species Reactivity

Human

SwissProt ID

O14901

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-274 of human KLF11 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:800-1500

Sensitivity	Endogenous	純度	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Transcription factor (PubMed:10207080, PubMed:9748269). Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth (PubMed:10207080, PubMed:16131492, PubMed:9748269). Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity). Induces apoptosis (By similarity)

Subcellular Localization：Nucleus

Expression：
Tissue_Specificity: Ubiquitous. Higher expression in erythroid cells
Induction: By TGFB1

Isoforms & Post-Translational Modification：O14901 has two isomers: O14901-1: 55139 Da (predicted); O14901-2: 53329 Da (predicted).

Subunit：Interacts with SIN3A

Synonyms

FKLF; FKLF1; MODY7; TIEG2; Tieg3

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/l132-cell.html [Content Brief]