KLRG1 Antibody (YA9701)
(Synonyms: 2F1 Ag, 2F1, C type lectin domain family 15 member A, C-type lectin domain family 15 member A, CLEC15A, ITIM containing receptor MAFA L, ITIM-containing receptor MAFA-L, Killer cell lectin like receptor G1, Killer cell lectin like receptor subfamily G member 1, Killer cell lectin-like receptor subfamily G member 1)KLRG1 Antibody (YA9701) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to KLRG1.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB
-
Reactivity :
Human, Rat, Mouse
-
Formulation:
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:1000 |
Product Details
KLRG1 Antibody (YA9701) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to KLRG1.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman, Rat, Mouse
-
Calculated Molecular Weight Predicted band size: 22 kDa;
Synthetic peptide of human KLRG1 (aa 1-38).
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
KLRG1 plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells
-
Subcellular Localization
Cell membrane
-
Expression
Tissue_Specificity: Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
Induction: By pathogens and viruses infections. -
Isoforms & Post-Translational Modification
KLRG1 has 2 isoforms, Q96E93-1: amino acid length is 195, molecular weight is 21831 Da (predicted); Q96E93-2: amino acid length is 189, molecular weight is 21206 Da (predicted).
-
Subunit
Forms a monomer and homodimer; disulfide-linked.
-
SwissProt ID
-
Synonyms
2F1 Ag, 2F1, C type lectin domain family 15 member A, C-type lectin domain family 15 member A, CLEC15A, ITIM containing receptor MAFA L, ITIM-containing receptor MAFA-L, Killer cell lectin like receptor G1, Killer cell lectin like receptor subfamily G member 1, Killer cell lectin-like receptor subfamily G member 1
Documentation