KYNU Antibody (YA8214)(PBS only)
(Synonyms: KYNUU)KYNU Antibody (YA8214) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to KYNU.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-4000 | 1:150-500 |
Product Details
KYNU Antibody (YA8214) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to KYNU.
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Host Mouse
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Species ReactivityHuman, Rat
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Calculated Molecular Weight Predicted band size: 34.5 kDa
Human recombinant protein fragment corresponding to amino acids 1-216 of human KYNU produced in E.coli.
Affinity purified
Non-conjugated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KYNU catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity
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Subcellular Localization
Cytoplasm, cytosol
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Expression
Tissue_Specificity: Expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas). Highest levels found in placenta, liver and lung. Expressed in all brain regions
Induction: Increased levels in several cerebral and systemic inflammatory conditions -
Isoforms & Post-Translational Modification
Q16719 has two isomers: Q16719-1: 52352 Da (predicted); Q16719-2: 34635 Da (predicted).
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Subunit
Homodimer
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SwissProt ID
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Synonyms
KYNUU
Documentation
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