KYNU Antibody (YA8214)(PBS only)

Cat. No.: HY-P88530A: Fiche technique User Guide for Antibodies
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Technical Support

KYNU Antibody (YA8214) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to KYNU.

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

* Veuillez sélectionner la quantité avant d'ajouter des articles.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description
Références

Description

KYNU Antibody (YA8214) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to KYNU.

Host

Mouse

Masse moléculaire

Predicted band size: 34.5 kDa

Species Reactivity

Human, Rat

SwissProt ID

Q16719

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-216 of human KYNU produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Pureté	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity

Subcellular Localization：Cytoplasm, cytosol

Expression：
Tissue_Specificity: Expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas). Highest levels found in placenta, liver and lung. Expressed in all brain regions
Induction: Increased levels in several cerebral and systemic inflammatory conditions

Isoforms & Post-Translational Modification：Q16719 has two isomers: Q16719-1: 52352 Da (predicted); Q16719-2: 34635 Da (predicted).

Subunit：Homodimer

Synonyms

KYNUU

Documentation

User Guide for Antibodies (1077 KB)

Références

[1]. /biology-dictionary/a549-cell.html [Content Brief]