LAMA4 Antibody (YA7896)
(Synonyms: CMD1JJ; LAMA3; LAMA4 -1; LAMA4*-1)LAMA4 Antibody (YA7896) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LAMA4.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
LAMA4 Antibody (YA7896) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LAMA4.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 199.8 kDa
Human recombinant protein fragment corresponding to amino acids 25-270 of human LAMA4 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
LAMA4 is a Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components
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Subcellular Localization
Secreted, extracellular space, extracellular matrix, basement membrane,Secreted
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Expression
Tissue_Specificity: Detected in placenta (at protein level) (PubMed:32337544). Detected in fibroblasts and urine (at protein level) (PubMed:25326458, PubMed:36213313, PubMed:37453717). In adult, strong expression in heart, lung, ovary small and large intestines, placenta, liver; weak or no expression in skeletal muscle, kidney, pancreas, testis, prostate, brain. High expression in fetal lung and kidney. Expression in fetal and newborn tissues is observed in certain mesenchymal cells in tissues such as smooth muscle and dermis -
Isoforms & Post-Translational Modification
Q16363 has three isomers: Q16363-1: 202568 Da (predicted); Q16363-2: 201820 Da (predicted); Q16363-3: 12819 Da (predicted).
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Subunit
Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end
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SwissProt ID
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Synonyms
CMD1JJ; LAMA3; LAMA4 -1; LAMA4*-1
Documentation