LAMA4 Antibody (YA7896)

Cat. No.: HY-P88212: Data Sheet User Guide for Antibodies
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LAMA4 Antibody (YA7896) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LAMA4.

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

LAMA4 Antibody (YA7896) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LAMA4.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 199.8 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q16363

Immunogen

Human recombinant protein fragment corresponding to amino acids 25-270 of human LAMA4 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components

Subcellular Localization：Secreted, extracellular space, extracellular matrix, basement membrane,Secreted

Expression：
Tissue_Specificity: Detected in placenta (at protein level) (PubMed:32337544). Detected in fibroblasts and urine (at protein level) (PubMed:25326458, PubMed:36213313, PubMed:37453717). In adult, strong expression in heart, lung, ovary small and large intestines, placenta, liver; weak or no expression in skeletal muscle, kidney, pancreas, testis, prostate, brain. High expression in fetal lung and kidney. Expression in fetal and newborn tissues is observed in certain mesenchymal cells in tissues such as smooth muscle and dermis

Isoforms & Post-Translational Modification：Q16363 has three isomers: Q16363-1: 202568 Da (predicted); Q16363-2: 201820 Da (predicted); Q16363-3: 12819 Da (predicted).

Subunit：Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end

Synonyms

CMD1JJ; LAMA3; LAMA4 -1; LAMA4*-1

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/mda-mb-435-cell.html [Content Brief]