LDLR Antibody (YA7411)
(Synonyms: Low-density lipoprotein receptor, LDL receptor, Ldlr)LDLR Antibody (YA7411) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to LDLR.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P, ICC/IF, ELISA
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|---|
| Dilution Ratio | 1:1000-1:4000 | 1:2000-1:10000 | 1:200-1:1000 | 1:5000-1:20000 |
Product Details
LDLR Antibody (YA7411) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to LDLR.
-
Host Rabbit
-
Clonality Monoclonal,Recombinant
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 130 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 95 kDa
The exact sequence is proprietary to MCE.
Endogenous
Protein A affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
The low-density lipoprotein receptor (LDLR) gene family includes LDLR, very LDLR, and LDL receptor-related proteins (LRPs) such as LRP1, LRP1b (aka LRP-DIT), LRP2 (aka megalin), LRP4, and LRP5/6, and LRP8 (aka ApoER2) . LDLR family members constitute a class of closely related multifunctional, transmembrane receptors, with diverse functions, from embryonic development to cancer, lipid metabolism, and cardiovascular homeostasis.
-
Subcellular Localization
Cell membrane,Membrane, clathrin-coated pit,Golgi apparatus,Early endosome,Late endosome,Lysosome
-
Isoforms & Post-Translational Modification
P01130 has 6 isomers: P01130-1: 95376 Da (predicted); P01130-2: 75854 Da (predicted); P01130-3: 76856 Da (predicted); P01130-4: 90940 Da (predicted); P01130-5: 95092 Da (predicted); P01130-6: 82255 Da (predicted).
N- and O-glycosylated丨Ubiquitinated by MYLIP leading to degradation -
Subunit
Interacts (via NPXY motif) with DAB2 (via PID domain); the interaction is impaired by tyrosine phosphorylation of the NPXY motif (By similarity)
-
SwissProt ID
-
Synonyms
Low-density lipoprotein receptor, LDL receptor, Ldlr
Documentation
Powered by Bioz
