LYPD3 Antibody (YA5979)
(Synonyms: LYPD3; C4.4A; UNQ491/PRO1007; Ly6/PLAUR domain-containing protein 3 ; GPI-anchored metastasis-associated protein C4.4A homolog; Matrigel-induced gene C4 protein; MIG-C4; )LYPD3 Antibody (YA5979) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LYPD3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IP
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Reactivity :
Human
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Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IP
IP: Immunoprecipitation
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|---|---|---|---|
| Dilution Ratio | 1:1000-5000 | 1:100-300 | 1:50-100 |
Product Details
LYPD3 Antibody (YA5979) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LYPD3.
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Host Rabbit
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 38 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
LYPD3 supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression
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Subcellular Localization
Cell membrane; Lipid-anchor, GPI-anchor
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Expression
Tissue_specificity:It is expressed in the placenta, skin, and urothelial cells. It is found in keratinocytes in the basal layer of chronic wounds. It is weakly expressed in esophageal and peripheral blood mononuclear cells. It is found in most primary and metastatic transitional cell carcinomas (TCCs) and breast cancer tissues, but not in adjacent normal tissues. High expression is found in tumor components of some non-invasive superficial lesions, as well as in invasive and metastatic urothelial carcinomas.
Induction:Up-regulated in migrating keratinocytes during epithelization of incisional skin wounds -
Subunit
Binds laminin-1 and laminin-5. Interacts with LGALS3 (By similarity). Interacts with AGR2 and AGR3
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SwissProt ID
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Synonyms
LYPD3; C4.4A; UNQ491/PRO1007; Ly6/PLAUR domain-containing protein 3 ; GPI-anchored metastasis-associated protein C4.4A homolog; Matrigel-induced gene C4 protein; MIG-C4;
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