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  4. Monoclonal Antibodies Recombinant Antibodies
  5. Mannan Binding Lectin/MBL Antibody (YA7134)

Mannan Binding Lectin/MBL Antibody (YA7134)

Cat. No.: HY-P87447
User Guide for Antibodies Technical Support

Mannan Binding Lectin/MBL Antibody (YA7134) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mannan Binding Lectin/MBL.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

Mannan Binding Lectin/MBL Antibody (YA7134) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mannan Binding Lectin/MBL.
Host

Rabbit
Clonality

Recombinant
Molecular Weight

Predicted band size: 26kDa;
Species Reactivity
Mouse
SwissProt ID
Immunogen

KLH conjugated synthetic peptide derived from human Mannan Binding Lectin
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1000
Sensitivity Endogenous Purity affinity purified by Protein A
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in PBS, Glycerol, BSA.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Calcium-dependent lectin involved in innate immune defense (PubMed:35102342). Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. Upon SARS coronavirus-2/SARS-CoV-2 infection, activates the complement lectin pathway which leads to the inhibition SARS-CoV-2 infection and a reduction of the induced inflammatory response (PubMed:35102342)
Subcellular Localization：Secreted
Expression：
Tissue_Specificity: Plasma protein produced mainly in the liver
Isoforms & Post-Translational Modification：P11226: 248 amino acids, molecular weight 26144 Da.
Subunit：Oligomeric complex of 3 or more homotrimers
Documentation
User Guide for Antibodies (1077 KB)

Mannan Binding Lectin/MBL Antibody (YA7134) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Mannan Binding Lectin/MBL Antibody (YA7134)
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