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MFGE8 Antibody (YA6899)

(Synonyms: BA46 antibody)
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MFGE8 Antibody (YA6899) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MFGE8.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
  • MFGE8 Antibody (YA6899) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:1000

Product Details

Description

MFGE8 Antibody (YA6899) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MFGE8.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 43 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size：43 kDa
Immunogen

Recombinant protein within human MFGE8 aa 1-387.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    MFGE8 plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization. Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction|Main constituent of aortic medial amyloid

  • Subcellular Localization

    Membrane,Secreted,Cytoplasmic vesicle, secretory vesicle, acrosome membrane

  • Expression


    Tissue_Specificity: Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas

  • Isoforms & Post-Translational Modification

    Q08431 has four isomers: Q08431-1: 43105 Da (predicted); Q08431-2: 31185 Da (predicted); Q08431-3: 37505 Da (predicted); Q08431-4: 38344 Da (predicted).
    Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273

  • SwissProt ID

    Q08431

  • Synonyms

    BA46 antibody

MFGE8 Antibody (YA6899) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • MFGE8 Antibody (YA6899) Product Image
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  • MFGE8 Antibody (YA6899) Product Image