MKLP1 Antibody (YA7291)
(Synonyms: KNSL5, MKLP1, KIF23, Kinesin-like protein KIF23, Kinesin-like protein 5, Mitotic kinesin-like protein 1)MKLP1 Antibody (YA7291) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MKLP1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in 0.01M tris buffered saline (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:500-1000 |
Product Details
MKLP1 Antibody (YA7291) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MKLP1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman Predicted Reactivity: Human
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Calculated Molecular Weight Predicted band size: 110 kDa;
KLH conjugated synthetic peptide derived from human MKLP1
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 0.01M tris buffered saline (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MKLP1 component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro
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Subcellular Localization
Nucleus,Cytoplasm, cytoskeleton, spindle,Midbody, Midbody ring
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Expression
Tissue_Specificity: Widely expressed -
Isoforms & Post-Translational Modification
Q02241 has three isomers: Q02241-1: 110059 Da (predicted); Q02241-2: 98105 Da (predicted); Q02241-3: 77699 Da (predicted).
Ubiquitinated -
Subunit
Heterotetramer of two molecules each of RACGAP1 and KIF23
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SwissProt ID
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Synonyms
KNSL5, MKLP1, KIF23, Kinesin-like protein KIF23, Kinesin-like protein 5, Mitotic kinesin-like protein 1
Documentation
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