NAB2 Antibody (YA8366)
(Synonyms: MADER)NAB2 Antibody (YA8366) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NAB2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
NAB2 Antibody (YA8366) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NAB2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 56.4 kDa
Human recombinant protein fragment corresponding to amino acids 178-442 of human NAB2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NAB2 acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Widely expressed at low levels. Highly expressed in melanoma cell lines
Induction: By serum and phorbol myristate acetate (PMA) stimulation -
Isoforms & Post-Translational Modification
Q15742 has three isomers: Q15742-1: 56594 Da (predicted); Q15742-2: 34356 Da (predicted); Q15742-3: 49748 Da (predicted).
Sumoylation by EGR2 represses EGR2 transcriptional activity in hindbrain -
Subunit
Homomultimers may associate with EGR1 bound to DNA
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SwissProt ID
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Synonyms
MADER
Documentation
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