NABP1 Antibody (YA8241)

Cat. No.: HY-P88557: Data Sheet User Guide for Antibodies
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NABP1 Antibody (YA8241) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to NABP1.

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

NABP1 Antibody (YA8241) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to NABP1.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 22.2 kDa

Species Reactivity

Human

SwissProt ID

Q96AH0

Immunogen

Full length human recombiant protein of human NABP1 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:500-800

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways

Subcellular Localization：Nucleus

Isoforms & Post-Translational Modification：Q96AH0 has three isomers: Q96AH0-1: 22423 Da (predicted); Q96AH0-2: 13579 Da (predicted); Q96AH0-3: 14677 Da (predicted).

Subunit：Component of the SOSS complex, composed of SOSS-B (SOSS-B1/NABP2 or SOSS-B2/NABP1), SOSS-A/INTS3 and SOSS-C/INIP

Synonyms

OBFC2A; SOSS-B2; SSB2

Documentation

User Guide for Antibodies (1077 KB)