NABP1 Antibody (YA8241)
(Synonyms: OBFC2A; SOSS-B2; SSB2)NABP1 Antibody (YA8241) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to NABP1.
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Host:
Mouse
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:500-800 |
Product Details
NABP1 Antibody (YA8241) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to NABP1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 22.2 kDa
Full length human recombiant protein of human NABP1 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NABP1 component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
Q96AH0 has three isomers: Q96AH0-1: 22423 Da (predicted); Q96AH0-2: 13579 Da (predicted); Q96AH0-3: 14677 Da (predicted).
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Subunit
Component of the SOSS complex, composed of SOSS-B (SOSS-B1/NABP2 or SOSS-B2/NABP1), SOSS-A/INTS3 and SOSS-C/INIP
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SwissProt ID
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Synonyms
OBFC2A; SOSS-B2; SSB2
Documentation
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