NGDN Antibody (YA8755)
(Synonyms: C14orf120; CANu1; LCP5; lpd-2; NGD)NGDN Antibody (YA8755) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NGDN.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
NGDN Antibody (YA8755) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NGDN.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 35.7 kDa
Full length human recombinant protein of human NGDN produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NGDN is a Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Its dissociation from the complex determines the transition from state pre-A1 to state pre-A1*. Inhibits mRNA translation in a cytoplasmic polyadenylation element (CPE)-dependent manner[1].
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Subcellular Localization
Nucleus,Nucleus, nucleolus,Chromosome, centromere,Cytoplasm,Cell projection, axon,Cell projection, dendrite,Cell projection, filopodium
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Isoforms & Post-Translational Modification
Q8NEJ9 has two isomers: Q8NEJ9-1: 35894 Da (predicted); Q8NEJ9-2: 35250 Da (predicted).
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Subunit
Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3 (PubMed:34516797)
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SwissProt ID
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Synonyms
C14orf120; CANu1; LCP5; lpd-2; NGD
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