nNOS Antibody (YA7193)

Cat. No.: HY-P87509: Data Sheet User Guide for Antibodies
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nNOS Antibody (YA7193) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to nNOS.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

nNOS Antibody (YA7193) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to nNOS.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 130 kDa;

Species Reactivity

Rat

SwissProt ID

P29475

Immunogen

KLH conjugated synthetic peptide derived from human nNOS

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000

Sensitivity	Endogenous	Purity	affinity purified by Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Solution

Formulation

Supplied in 0.01M tris buffered saline (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR

Subcellular Localization：Cell membrane, sarcolemma,Cell projection, dendritic spine

Expression：
Tissue_Specificity: Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3 is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in the brain, but not in the heart and adrenal gland

Isoforms & Post-Translational Modification：P29475 has 5 isomers: P29475-1: 160970 Da (predicted); P29475-2: 148919 Da (predicted); P29475-3: 125113 Da (predicted); P29475-4: 43838 Da (predicted); P29475-5: 164779 Da (predicted).
Ubiquitinated; mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro)

Subunit：Homodimer

Synonyms

Nitric oxide synthase 1, Constitutive NOS, NC-NOS, NOS type I, Neuronal NOS, Peptidyl-cysteine S-nitrosylase NOS1, N-NOS, nNOS, bNOS, NOS1

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/a-375-cell.html [Content Brief]