NR2E1 Antibody (YA2648)

Cat. No.: HY-P82903: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

NR2E1 Antibody (YA2648) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NR2E1.

For research use only. We do not sell to patients.

Size	Stock	Quantity
Free Sample	Apply now
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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NR2E1 Antibody (YA2648) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

NR2E1 Antibody (YA2648) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NR2E1.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 43 kDa;

Observed band size: 48 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9Y466

Gene ID

7101 [NCBI]

Immunogen

A synthesized peptide derived from human NR2E1 aa10-42.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acid receptor (RAR) regulation in retinal cells

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:Brain specific. Present in all brain sections tested, highest levels in the caudate nucleus and hippocampus, weakest levels in the thalamus

Isoforms & Post-Translational Modification：Q9Y466 has 2 isomers: Q9Y466-1: 42589 Da (predicted); Q9Y466-2: 46400 Da (predicted).

Subunit：Monomer. Interacts with ATN1; the interaction represses the transcription

RRID

AB_3104995

Database

Entrez Gene: 7101 Human ; 21907 Mouse ; 684085 Rat

SwissProt: Q9Y466 Human ; Q3UXE8 Mouse ; Q64104 Mouse ;

OMIM: 603849 Human

Research Field

Neuroscience

Synonyms

hTll; nr2e1; Tll; TLX; XTLL

Documentation

Select Batch:

Data Sheet (231 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

NR2E1 Antibody (YA2648) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NR2E1 Antibody (YA2648)

NR2E1 Antibody (YA2648) Featured Recommendations:

Product Detail

Background

Documentation

NR2E1 Antibody (YA2648) Related Classifications

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