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  3. Monoclonal Antibodies Recombinant Antibodies
  4. NR2E1 Antibody (YA2648)

NR2E1 Antibody (YA2648) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NR2E1.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay
  • Product Detail

  • Background

  • Descripciòn

Descripciòn

NR2E1 Antibody (YA2648) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NR2E1.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Peso molecular
Predicted band size: 43 kDa;
Observed band size: 48 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human NR2E1 aa10-42.

Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Pureza Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid

Formulation

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background
Function:Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acid receptor (RAR) regulation in retinal cells
Subcellular Localization:Nucleus
Expression:
Tissue_specificity:Brain specific. Present in all brain sections tested, highest levels in the caudate nucleus and hippocampus, weakest levels in the thalamus
Isoforms & Post-Translational Modification:Q9Y466 has 2 isomers: Q9Y466-1: 42589 Da (predicted); Q9Y466-2: 46400 Da (predicted).
Subunit:Monomer. Interacts with ATN1; the interaction represses the transcription
RRID
Database
Research Field

Neuroscience

Synonyms
hTll; nr2e1; Tll; TLX; XTLL
Documentación

NR2E1 Antibody (YA2648) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
NR2E1 Antibody (YA2648)
Cat. No.:
HY-P82903
Cantidad:
MCE Japan Authorized Agent: