NR2F2 Antibody (YA1223)(PBS only)

Cat. No.: HY-P81478A: Fiche technique User Guide for Antibodies
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NR2F2 Antibody (YA1223) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NR2F2.

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

* Veuillez sélectionner la quantité avant d'ajouter des articles.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description

Description

NR2F2 Antibody (YA1223) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NR2F2.

Host

Rabbit

Masse moléculaire

Predicted band size: 46 kDa;

Observed band size: 46 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P24468

Gene ID

7026 [NCBI]

Immunogen

A synthesized peptide derived from human NR2F2

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	100-1:200

Pureté	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. May be required to establish ovary identity during early gonad development (PubMed:29478779)

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:Ubiquitous. Expressed in the stromal cells of developing fetal ovaries (PubMed:29478779)

Isoforms & Post-Translational Modification：P24468 has 3 isomers: P24468-1: 45571 Da (predicted); P24468-2: 31484 Da (predicted); P24468-3: 29163 Da (predicted).

Subunit：Interacts with SQSTM1 (By similarity). Binds DNA as a dimer; homodimer or heterodimer with NR2F6. Interacts with NCOA1, NCOA2, NCOA3 and PPARGC1A. Interacts with ZFPM2 (By similarity)

Research Field

Epigenetics and Nuclear Signaling

Synonyms

NR2F2; ARP1; TFCOUP2; COUP transcription factor 2; COUP-TF2; Apolipoprotein A-I regulatory protein 1; ARP-1; COUP transcription factor II; COUP-TF II; Nuclear receptor subfamily 2 group F member 2

Documentation

User Guide for Antibodies (1077 KB)