NRBF2 Antibody (YA8703)(PBS only)

Cat. No.: HY-P89019A: Data Sheet User Guide for Antibodies
FAQs
Technical Support

NRBF2 Antibody (YA8703) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NRBF2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

NRBF2 Antibody (YA8703) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NRBF2.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q96F24

Immunogen

Full length human recombinant protein of human NRBF2 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-500

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro)|Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). However, effects has been described variably. Involved in the induction of starvation-induced autophagy (PubMed:24785657). Stabilizes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3 (By similarity). Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1 (PubMed:25086043). May be involved in autophagosome biogenesis (PubMed:25086043). May play a role in neural progenitor cell survival during differentiation (By similarity)

Subcellular Localization：Nucleus,Cytoplasm,Cytoplasmic vesicle,Cytoplasmic vesicle, autophagosome

Expression：
Tissue_Specificity: Detected in keratinocytes, liver and placenta (PubMed:15610520). Expressed in a subset of cells in pediatric medulloblastoma (PubMed:18619852)

Isoforms & Post-Translational Modification：Q96F24 has three isomers: Q96F24-1: 32378 Da (predicted); Q96F24-2: 26955 Da (predicted); Q96F24-3: 31001 Da (predicted).

Subunit：Interacts with PPARA, PPARD and PPARG

Synonyms

COPR; COPR1; COPR2; NRBF-2

Documentation

User Guide for Antibodies (1077 KB)