NSD1 Antibody (YA5137)
(Synonyms: NSD1; ARA267; KMT3B; Histone-lysine N-methyltransferase; H3 lysine-36 and H4 lysine-20 specific; Androgen receptor coactivator 267 kDa protein; Androgen receptor-associated protein of 267 kDa; H3-K36-HMTase; H4-K20-HMTase; Lysine N-methyltr)NSD1 Antibody (YA5137) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to NSD1.
-
Host:
Mouse
-
Application:
WB
-
Reactivity :
Human
-
Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:1000-1:2000 |
Product Details
NSD1 Antibody (YA5137) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to NSD1.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Calculated Molecular Weight Predicted band size: 297 kDa;
Purified recombinant human NSD1 protein fragments expressed in E.coli.
affinity purified.
Non-conjugated
Unmodified
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
NSD1 is a Histone methyltransferase that dimethylates Lys-36 of histone H3 (H3K36me2). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context
-
Subcellular Localization
Nucleus; Chromosome
-
Expression
Tissue_specificity:Expressed in the fetal/human brain, kidney, skeletal muscle, spleen, and the thymus, and faintly in the lung -
Isoforms & Post-Translational Modification
Q96L73 has 3 isomers: Q96L73-1: 296652 Da (predicted); Q96L73-2: 267340 Da (predicted); Q96L73-3: 284264 Da (predicted).
-
Subunit
Interacts with the ligand-binding domains of RARA and THRA in the absence of ligand; in the presence of ligand the interaction is severely disrupted but some binding still occurs. Interacts with the ligand-binding domains of RXRA and ESRRA only in the presence of ligand. Interacts with ZNF496 (By similarity). Interacts with AR DNA- and ligand-binding domains
-
SwissProt ID
-
Synonyms
NSD1; ARA267; KMT3B; Histone-lysine N-methyltransferase; H3 lysine-36 and H4 lysine-20 specific; Androgen receptor coactivator 267 kDa protein; Androgen receptor-associated protein of 267 kDa; H3-K36-HMTase; H4-K20-HMTase; Lysine N-methyltr
Documentation
Powered by Bioz
