NXNL1 Antibody
(Synonyms: nucleoredoxin like 1; RDCVF; TXNL6; NXNL1)NXNL1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to P2RY13.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human
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Formulation:
Supplied in pH 7.4 PBS, 0.05% NaN3, 40% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 |
Product Details
NXNL1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to P2RY13.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 24 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 24 kDa
Fusion protein of human NXNL1.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in pH 7.4 PBS, 0.05% NaN3, 40% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NXNL1 is a Thioredoxin-like protein that protects retinal rod and cone photoreceptors against oxidative stress and photo-oxidative damage. Plays a role in the inhibition of TAU phosphorylation and protects TAU against oxidative stress in the retina (By similarity). Acts as a reducing system for MSRA, facilitating the repair of oxidized proteins such as alpha-crystallin (CRYAA/CRYAB) and cytochrome c (CYCS) in the lens during oxidative stress conditions[1].
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Subcellular Localization
Cytoplasm; Mitochondrion
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Expression
Tissue_Specificity: Expressed in the lens epithelium and fiber cells (at protein level). Expressed in the retina, stomach, kidney, heart, colon, and spleen.
Induction: By oxidative stress (at protein level). -
Isoforms & Post-Translational Modification
NXNL1 has 2 isoforms, Q96CM4-1: amino acid length is 212, molecular weight is 23943 Da (predicted); Q96CM4-2: amino acid length is 109, molecular weight is 12724 Da (predicted).
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Subunit
Interacts with isoform 1 of BSG
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SwissProt ID
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Synonyms
nucleoredoxin like 1; RDCVF; TXNL6; NXNL1
Documentation
References
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