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  4. Monoclonal Antibodies Recombinant Antibodies
  5. OGG1 Antibody (YA3356)

OGG1 Antibody (YA3356) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to OGG1.

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Top Publications Citing Use of Products

1 Publications Citing Use of MCE OGG1 Antibody (YA3356)

  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

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  • Descripciòn

Descripciòn

OGG1 Antibody (YA3356) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to OGG1.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Peso molecular
Predicted band size: 39 kDa;
Observed band size: 39 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human OGG1 aa300-345/345.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Pureza Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Envío

Shipping with blue ice.
Verification Image
WB

  • Western blot analysis of extracts from HepG2 (lane 2(20μg) and HepG2 (lane 3(40μg) using OGG1 (HY-P83611) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

Background
Function：DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion
Subcellular Localization：Nucleus, nucleoplasm; Nucleus speckle; Nucleus matrix; Nucleus; Mitochondrion
Expression：
Tissue_specificity:Ubiquitous
Isoforms & Post-Translational Modification：O15527 has 8 isomers: O15527-1: 38782 Da (predicted); O15527-2: 36433 Da (predicted); O15527-3: 45761 Da (predicted); O15527-4: 47237 Da (predicted); O15527-5: 39729 Da (predicted); O15527-6: 22210 Da (predicted); O15527-7: 40095 Da (predicted); O15527-8: 36085 Da (predicted).
RRID
Database

Entrez Gene: 4968 Human

SwissProt: O15527 Human

OMIM: 144700 Human

Research Field

Epigenetics and Nuclear Signaling
Synonyms
8 hydroxyguanine DNA glycosylase; AP lyase; HMMH; HOGG1; MMH; MUTM; N glycosylase; Ogg1; OGH 1
Documentación
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

OGG1 Antibody (YA3356) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
OGG1 Antibody (YA3356)
Cat. No.:
HY-P83611
Cantidad:
MCE Japan Authorized Agent:

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