PAPSS2 Antibody (YA8721)(PBS only)

Cat. No.: HY-P89037A: Data Sheet User Guide for Antibodies
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PAPSS2 Antibody (YA8721) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PAPSS2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

PAPSS2 Antibody (YA8721) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PAPSS2.

Host

Mouse

Molecular Weight

Predicted band size: 69.3 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

O95340

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-247 of human PAPSS2 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate/PAPS, the activated sulfate donor used by sulfotransferases (PubMed:11773860, PubMed:19474428, PubMed:23824674, PubMed:25594860). In mammals, PAPS is the sole source of sulfate while APS appears to only be an intermediate in the sulfate-activation pathway (PubMed:11773860, PubMed:19474428, PubMed:23824674, PubMed:25594860). Plays indirectly an important role in skeletogenesis during postnatal growth (PubMed:9771708)

Expression：
Tissue_Specificity: Expressed in cartilage and adrenal gland

Isoforms & Post-Translational Modification：O95340 has two isomers: O95340-1: 69501 Da (predicted); O95340-2: 69970 Da (predicted).

Synonyms

ATPSK2; BCYM4; SK2

Documentation

User Guide for Antibodies (1077 KB)