PDE4B Antibody (YA9988)
(Synonyms: DPDE4, PDE4B, PDE32, cAMP-specific phosphodiesterase 4B)PDE4B Antibody (YA9988) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to PDE4B.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH 7.4), containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
PDE4B Antibody (YA9988) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to PDE4B.
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Host Rabbit
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 100 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 83 kDa
Synthetic peptide corresponding to human PDE4B.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PDE4B hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents[1].
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Subcellular Localization
Cytoplasm; Cell membrane
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Expression
Tissue_Specificity: Expressed in brain, heart, lung and skeletal muscle. Expressed in white blood cells. -
Isoforms & Post-Translational Modification
PDE4B has 4 isoforms, Q07343-1: amino acid length is 736, molecular weight is 83343 Da (predicted); Q07343-2: amino acid length is 564, molecular weight is 64352 Da (predicted); Q07343-3: amino acid length is 721, molecular weight is 82096 Da (predicted); Q07343-4: amino acid length is 503, molecular weight is 57709 Da (predicted).
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Subunit
Interacts with DISC1
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SwissProt ID
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Synonyms
DPDE4, PDE4B, PDE32, cAMP-specific phosphodiesterase 4B
Documentation
References
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