PerCP-conjugated CD86 Antibody (BU63)
(Synonyms: CD86,CD86-PerCP,BU63)PerCP-conjugated CD86 Antibody (BU63) is a Mouse-derived and PerCP conjugated monoclonal antibody, targeting to CD86.
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Host:
Mouse
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Isotype:
Mouse IgG1,κ
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Application:
FC
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Conjugation:
PerCP
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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|---|---|
| Dilution Ratio | 5 ul per 106 cells in a 100 µl suspension |
Product Details
PerCP-conjugated CD86 Antibody (BU63) is a Mouse-derived and PerCP conjugated monoclonal antibody, targeting to CD86.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
PerCP
Unmodified
Mouse IgG1,κ
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Storage & Stability
Stored at 2-8°C for 1 year, protect from light, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
CD86 (B7-2) is an immune co-stimulatory molecule expressed on the surface of antigen-presenting cells that regulates T-cell activation through binding to CD28 or CTLA-4 on T cells; it serves as a classic marker in research concerning dendritic cell maturation, macrophage polarization, tumor immunity, autoimmunity, infection, and transplant immunology.
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:Expressed on activated B-cells -
Isoforms & Post-Translational Modification
CD86 has 2 isomers: P42082-1: 34666 Da (predicted); P42082-2: 33962 Da (predicted).
Polyubiquitinated; which is promoted by MARCH8 and results in endocytosis and lysosomal degradation -
Subunit
Homodimer. Interacts (via cytoplasmic domain) with PHB1 and PHB2; the interactions increases after priming with CD40.
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Synonyms
CD86,CD86-PerCP,BU63
Documentation
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