Phospho-PLM (Ser68) Antibody (YA10093)
(Synonyms: Dickkopf-related protein 2; Dickkopf-2; Dkk-2; hDkk-2)Phospho-PLM (Ser68) Antibody (YA10093) is a Mouse-derived and non-conjugated IgG1 Monoclonal antibody, targeting to Phospho-PLM (Ser68).
-
Host:
Mouse
-
Isotype:
IgG
-
Application:
WB
-
Reactivity :
Mouse
-
Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:1000-2000 |
Product Details
Phospho-PLM (Ser68) Antibody (YA10093) is a Mouse-derived and non-conjugated IgG1 Monoclonal antibody, targeting to Phospho-PLM (Ser68).
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityMouse
-
Observed Molecular WeightObserved band size: 8 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 10 kDa
Synthetic phosphopeptide corresponding to residues surrounding S68 of human PLM protein.
Endogenous
affinity purified.
Non-conjugated
Phosphorylated
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
Phospholemman (PLM) is a major target for phosphorylation mediated by both PKA (at Ser68) and PKC (at both Ser63 and Ser68) in the heart. In intact cardiac myocytes, PLM associates with and inhibits Na(+)-K(+)-ATPase (NKA), mainly by reducing its affinity for internal Na(+). The inhibition is relieved upon PLM phosphorylation by PKA or PKC.
-
Synonyms
Dickkopf-related protein 2; Dickkopf-2; Dkk-2; hDkk-2
Documentation
Powered by Bioz
