POMC Antibody (YA1619)

Cat. No.: HY-P81874: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

POMC Antibody (YA1619) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to POMC.

For research use only. We do not sell to patients.

Size	Stock	Quantity
Free Sample	Apply now
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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POMC Antibody (YA1619) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
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Background
Documentation

Description

POMC Antibody (YA1619) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to POMC.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 29 kDa;

Observed band size: 29 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P01189

Gene ID

5443 [NCBI]

Immunogen

A synthesized peptide derived from human POMC aa110-180/267.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IP IP: Immunoprecipitation	1:50

Sensitivity	Endogenous	Purity	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

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mIHC

Tyramide signaling amplification based immunofluorescence analysis of paraffin-embedded human pituitary adenoma tissue using POMC Antibody (YA1619). The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P81874, 1/200) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer and fluorescent tyramide signal amplification system.Immunostaining was performed with Vari Fluor 594 TSA (200×)（HY-D1835）. Tissues were counterstained with DAPI (blue) and mounted with Anti-fade fluorescence mounting medium.

Background

Function：Stimulates the adrenal glands to release cortisol; Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes; Increases the pigmentation of skin by increasing melanin production in melanocytes; Endogenous orexigenic opiate; Endogenous opiate

Subcellular Localization：Secreted

Expression：
Tissue_specificity:ACTH and MSH are secreted by the pituitary gland.

RRID

AB_3103972

Database

Entrez Gene: 5443 Human ; 18976 Mouse ;

SwissProt: P01189 Human ; P01193 Mouse ; P01194 Rat

OMIM: 601665 Human

Research Field

Neuroscience

Synonyms

Pro-opiomelanocortin; POMC; Corticotropin-lipotropin; NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone; ACTH); Melanotropin alpha (Alpha-MSH); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH); Beta-endorphin; Met-enkephalin

Documentation

Select Batch:

Data Sheet (234 KB) SDS (254 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

POMC Antibody (YA1619) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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POMC Antibody (YA1619)

POMC Antibody (YA1619) Featured Recommendations:

Product Detail

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Background

Documentation

POMC Antibody (YA1619) Related Classifications

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