PPAR Delta Antibody (YA7733)
PPAR Delta Antibody (YA7733) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to PPAR Delta.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, ICC/IF
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Formulation:
Supplied in 10mM TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-500 |
Product Details
PPAR Delta Antibody (YA7733) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to PPAR Delta.
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Host Mouse
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Clonality Monoclonal
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Calculated Molecular Weight Predicted band size: 48 kDa;
Recombinant human PPAR delta Protein
Endogenous
affinity purified by Protein G
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 10mM TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PPAR Delta is a Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand[1].
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Ubiquitous with maximal levels in placenta and skeletal muscle -
Isoforms & Post-Translational Modification
Q03181 has four isomers: Q03181-1: 49903 Da (predicted); Q03181-2: 40406 Da (predicted); Q03181-3: 45764 Da (predicted); Q03181-4: 38855 Da (predicted).
'Lys-48'-linked polyubiquitinated; leading to proteasomal degradation (PubMed:35675826) -
Subunit
Heterodimer with the retinoid X receptor
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SwissProt ID
Documentation
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