2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. RAB17 Antibody (YA8376)

RAB17 Antibody (YA8376) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RAB17.

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容量 価格（税別） 在庫状況
20 μL $115 見積もりとリードタイムを求めるのご確認
50 μL $185 見積もりとリードタイムを求めるのご確認
100 μL $300 見積もりとリードタイムを求めるのご確認

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 説明

製品説明

RAB17 Antibody (YA8376) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RAB17.
Host

Mouse
Clonality

Monoclonal
分子量

Predicted band size: 23.3 kDa
Species Reactivity
Human
SwissProt ID
Immunogen

Full length human recombinant protein of human RAB17 produced in HEK293T cell.
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-250
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:100-250
Sensitivity Endogenous 純度 Affinity purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG1  
Appearance

Liquid
Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
輸送条件

Shipping with blue ice.
Background
Function：The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB17 is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role in cell migration (PubMed:22328529)
Subcellular Localization：Recycling endosome membrane,Melanosome,Cell projection, dendrite
Expression：
Tissue_Specificity: Expressed in melanocytes (at protein level)
Induction: Up-regulated by forskolin probably through the transcription factor MITF
Isoforms & Post-Translational Modification：Q9H0T7 has two isomers: Q9H0T7-1: 23491 Da (predicted); Q9H0T7-2: 9394 Da (predicted).
Synonyms
FLJ12538
ドキュメンテーション
User Guide for Antibodies (1077 KB)

RAB17 Antibody (YA8376) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
RAB17 Antibody (YA8376)
製品番号:
HY-P88692
数量:
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