Rab4 Antibody (YA5249)
(Synonyms: HRES 1 / RAB4; Oncogene RAB4; OTTHUMP00000042824; Rab 4; RAB 4A; RAB4 member RAS oncogene family; RAB4A; RAB4A member RAS oncogene family; RAB4A_HUMAN; Ras related protein Rab 4A; Ras related protein Rab4A; Ras-related protein Rab-4A.)Rab4 Antibody (YA5249) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Rab4.
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Host:
Mouse
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Application:
WB
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Reactivity :
Human, Mouse, Rat, Monkey
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500 |
Product Details
Rab4 Antibody (YA5249) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Rab4.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat, Monkey
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Observed Molecular WeightObserved band size: 24 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Purified recombinant human RAB4A protein fragments expressed in E.coli.
affinity chromatography.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Rab4 is a The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB4A is involved in protein transport. Also plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling. Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets[1][2][3].
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Subcellular Localization
Membrane; Peripheral membrane protein; Cytoplasm; Early endosome membrane; Peripheral membrane protein; Recycling endosome membrane; Peripheral membrane protein
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Subunit
Interacts with SGSM1, SGSM2 and SGSM3 (By similarity). Interacts with RAB11FIP1, RABEP1, ZFYVE20 and RUFY1 (PubMed:10698684, PubMed:11786538, PubMed:11788822, PubMed:14617813, PubMed:15280022, PubMed:16034420).
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SwissProt ID
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Synonyms
HRES 1 / RAB4; Oncogene RAB4; OTTHUMP00000042824; Rab 4; RAB 4A; RAB4 member RAS oncogene family; RAB4A; RAB4A member RAS oncogene family; RAB4A_HUMAN; Ras related protein Rab 4A; Ras related protein Rab4A; Ras-related protein Rab-4A.
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