RASSF2 Antibody (YA1834)
(Synonyms: CENP-34; RASFADIN)RASSF2 Antibody (YA1834) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RASSF2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-1:1000 |
Product Details
RASSF2 Antibody (YA1834) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RASSF2.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 38 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 38 kDa
A synthetic peptide of human RASSF2
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
RASSF2 is a Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation
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Subcellular Localization
Nucleus; Cytoplasm; Chromosome, centromere, kinetochore
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Expression
Tissue_specificity:Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines -
Isoforms & Post-Translational Modification
P50749 has 2 isomers: P50749-1: 37790 Da (predicted); P50749-2: 17879 Da (predicted).
Phosphorylated by STK3/MST2 and STK4/MST1 -
Subunit
Interacts directly with activated KRAS in a GTP-dependent manner. Interacts (via SARAH domain) with STK3/MST2 and STK4/MST1
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SwissProt ID
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Synonyms
CENP-34; RASFADIN
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Research Field
Signal Transduction
Documentation
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