RFC4 Antibody (YA7827)
(Synonyms: A1; RFC37)RFC4 Antibody (YA7827) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RFC4.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Monkey, Mouse, Rat, Dog
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 |
Product Details
RFC4 Antibody (YA7827) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RFC4.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Monkey, Mouse, Rat, Dog
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Calculated Molecular Weight Predicted band size: 39.5 kDa
Full length human recombinant protein of human RFC4 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
RFC4 is a Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA. The RFC4 subunit probably functions as a scaffold on which the other complex components can assemble
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
P35249 has two isomers: P35249-1: 39682 Da (predicted); P35249-2: 33675 Da (predicted).
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Subunit
Subunit of the RFC complex, an heteropentameric complex consisting of a large subunit RFC1 and four small subunits RFC2, RFC3, RFC4 and RFC5; the RFC complex interacts with PCNA (PubMed:8999859, PubMed:9488738, PubMed:39106866)
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SwissProt ID
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Synonyms
A1; RFC37
Documentation