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RGS6 Antibody (YA3211)

(Synonyms: regulator of G protein signaling 6; GAP; S914; HA117)

RGS6 Antibody (YA3211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RGS6.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human

  • Formulation:

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Conjugation:
    Non-conjugated
  • RGS6 Antibody (YA3211) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

RGS6 Antibody (YA3211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RGS6.

  • Host Rabbit
  • Clonality Recombinant, Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 54 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 54 kDa
Species Reactivity Database

Entrez Gene: 9628 Human

SwissProt: P49758 Human

Immunogen

A synthetic peptide of human RGS6 aa443-455.

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    RGS6 regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity[1].

  • Subcellular Localization

    Cytoplasm; Cytoplasm, cytosol; Membrane; Peripheral membrane protein; Nucleus; Cell membrane

  • Isoforms & Post-Translational Modification

    P49758 has 15 isomers: P49758-4: 54423 Da (predicted); P49758-2: 56138 Da (predicted); P49758-3: 56512 Da (predicted); P49758-5: 53787 Da (predicted); P49758-6: 49520 Da (predicted); P49758-7: 50155 Da (predicted); P49758-8: 54049 Da (predicted); P49758-9: 52245 Da (predicted); P49758-10: 51870 Da (predicted); P49758-11: 49781 Da (predicted); P49758-12: 40588 Da (predicted); P49758-13: 54953 Da (predicted); P49758-14: 55270 Da (predicted); P49758-15: 55614 Da (predicted); P49758-16: 53319 Da (predicted).

  • Subunit

    Interacts with GNB5 (PubMed:10339615, PubMed:10521509, PubMed:12761221). Interacts with GNAI1 (PubMed:18434541)

  • SwissProt ID

    P49758

  • Gene ID
    9628 [NCBI]
  • Synonyms

    regulator of G protein signaling 6; GAP; S914; HA117

  • Research Field

    -

RGS6 Antibody (YA3211) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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