Copy Link Print Information

RNA Polymerase beta Antibody (YA2403)

(Synonyms: groN; nitB; rif; RNA pol beta; RNA polymerase subunit beta; ron; rpoB; stl; stv; tabD; Transcriptase subunit beta)
Customer Review

Based on 1 Customer Validation

RNA Polymerase beta Antibody (YA2403) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RNA Polymerase beta.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IP

  • Reactivity :

    E.coli

  • Formulation:

    1.Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
    2.Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
    Please refer to the lot-specific COA for specific buffer information.

  • Conjugation:
    Non-conjugated
  • RNA Polymerase beta Antibody (YA2403) Product Image
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Service
Data Download
Related Products:
Top Publications Citing

Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:1000-1:2000 1:20

Product Details

Description

RNA Polymerase beta Antibody (YA2403) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RNA Polymerase beta.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    E.coli
  • Observed Molecular Weight
    Observed band size: 151 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 151 kDa
Species Reactivity Database

Entrez Gene: 948488 E.coli

SwissProt: P0A8V2 E.coli

Immunogen

A synthesized peptide derived from RNA polymerase beta aa1300-1342/1342.

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3104758

Product Properties

  • Appearance

    Liquid

  • Formulation

    1.Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
    2.Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
    Please refer to the lot-specific COA for specific buffer information.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    RNA Polymerase beta is a DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Resistance to the antibiotics salinamide A, salinamide B, rifampicin, streptolydigin, CBR703, myxopyronin, and lipiarmycin can result from mutations in this protein; Part of the processive rRNA transcription and antitermination complex (rrnTAC). The complex forms an RNA-chaperone ring around the RNA exit tunnel of RNAP. It supports rapid transcription and antitermination of rRNA operons, cotranscriptional rRNA folding, and annealing of distal rRNA regions to allow correct ribosome biogenesis

  • Subunit

    The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. The rRNA transcription and antitermination complex (rrnTAC) consists of RNAP, NusA, NusB, NusE (rpsJ), NusG, SubB, ribosomal protein S4, DNA and precursor rRNA; S4 is more flexible than other subunits (PubMed:32871103). In pull-down experiments interacts with CedA (PubMed:28818726)

  • SwissProt ID

    P0A8V2

  • Gene ID
    948488 [NCBI]
  • Synonyms

    groN; nitB; rif; RNA pol beta; RNA polymerase subunit beta; ron; rpoB; stl; stv; tabD; Transcriptase subunit beta

  • Research Field

    Epigenetics and Nuclear Signaling

RNA Polymerase beta Antibody (YA2403) Related Classifications

MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00

Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • RNA Polymerase beta Antibody (YA2403) Product Image
    1/16
  • RNA Polymerase beta Antibody (YA2403) Product Image