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  4. Monoclonal Antibodies Recombinant Antibodies
  5. Sarcomeric alpha Actinin Antibody (YA1903)

Sarcomeric alpha Actinin Antibody (YA1903)

Cat. No.: HY-P82158
User Guide for Antibodies Technical Support

Sarcomeric alpha Actinin Antibody (YA1903) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Sarcomeric alpha Actinin.

For research use only. We do not sell to patients.

Size Price Stock Quantity
20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

Sarcomeric alpha Actinin Antibody (YA1903) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Sarcomeric alpha Actinin.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Molecular Weight
Predicted band size: 104 kDa;
Observed band size: 104 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human Sarcomeric Alpha Actinin aa1-14.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
IP
IP: Immunoprecipitation
1:20
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein
Subcellular Localization：Cytoplasm, myofibril, sarcomere, Z line
Expression：
Tissue_specificity:It is expressed in both skeletal muscle and cardiac muscle.
Isoforms & Post-Translational Modification：P35609 has 2 isomers: P35609-1: 103854 Da (predicted); P35609-2: 103920 Da (predicted).
Ubiquitinated by FBXL22, leading to proteasomal degradation
Subunit：Homodimer; antiparallel. Also forms heterodimers with ACTN3. Interacts with ADAM12, MYOZ1, MYOZ2 and MYOZ3. Interacts via its C-terminal region with the LDB3 PDZ domain. Interacts with XIRP2. Interacts with DST isoform 1 (via N-terminus). Interacts with PARVB. Interacts with SYNPO2
Database

Entrez Gene: 88 Human ; 11472 Mouse ; 291245 Rat

SwissProt: P35609 Human ; Q9JI91 Mouse ;

OMIM: 612158 Human

Research Field

Signal Transduction
Synonyms
Actin binding protein; Actinin alpha 2; ACTN2; Alpha actinin 2; CMD1AA
Documentation
User Guide for Antibodies (1077 KB)

Sarcomeric alpha Actinin Antibody (YA1903) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Sarcomeric alpha Actinin Antibody (YA1903)
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