SGK196 Antibody (YA8707)

Cat. No.: HY-P89023: Ficha de datos User Guide for Antibodies
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SGK196 Antibody (YA8707) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SGK196.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

SGK196 Antibody (YA8707) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SGK196.

Host

Mouse

Clonality

Monoclonal

Peso molecular

Predicted band size: 39.9 kDa

Species Reactivity

Human

SwissProt ID

Q9H5K3

Immunogen

Human recombinant protein fragment corresponding to amino acids 141-350 of human SGK196 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	Pureza	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif

Subcellular Localization：Endoplasmic reticulum membrane

Expression：
Tissue_Specificity: Highest expression is observed in brain, skeletal muscle, kidney and heart in fetal and adult tissues

Isoforms & Post-Translational Modification：Q9H5K3: 350 amino acids, molecular weight 40050 Da.

Synonyms

MDDGA12; MDDGC12; SGK196

Documentación

User Guide for Antibodies (1077 KB)