SHPRH Antibody (YA9961)
(Synonyms: bA545I5.2)SHPRH Antibody (YA9961) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SHPRH.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:1000-2000 |
Product Details
SHPRH Antibody (YA9961) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SHPRH.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 192.9 kDa
Human recombinant protein fragment corresponding to amino acids 1-100 and 1500
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SHPRH is an E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'
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Expression
Tissue_Specificity: Broadly expressed. -
Isoforms & Post-Translational Modification
SHPRH has 4 isoforms, Q149N8-1: amino acid length is 1683, molecular weight is 193079 Da (predicted); Q149N8-2: amino acid length is 929, molecular weight is 107341 Da (predicted); Q149N8-4: amino acid length is 1659, molecular weight is 190497 Da (predicted); Q149N8-5: amino acid length is 471, molecular weight is 54339 Da (predicted).
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Subunit
Homodimer.
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SwissProt ID
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Synonyms
bA545I5.2
Documentation
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