SLC39A5 Antibody (YA8179)

Cat. No.: HY-P88495: Data Sheet User Guide for Antibodies
FAQs
Technical Support

SLC39A5 Antibody (YA8179) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC39A5.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명
References

제품 설명

SLC39A5 Antibody (YA8179) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC39A5.

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 56.1 kDa

Species Reactivity

Human

SwissProt ID

Q6ZMH5

Immunogen

Human recombinant protein fragment corresponding to amino acids 48-178 of human SLC39A5 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:500-800

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Uniporter that transports zinc(2+) into polarized cells of enterocytes, pancreatic acinar and endoderm cells across the basolateral membrane and participates, notably, in zinc excretion from the intestine by the uptake of zinc from the blood into the intestine (By similarity). The transport mechanism is temperature- and concentration-dependent and saturable (By similarity). In addition, is also a high affinity copper transporter in vitro (PubMed:36454509). Also may regulate glucose-stimulated insulin secretion (GSIS) in islets primarily through the zinc-activated SIRT1-PPARGC1A axis (By similarity). Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera (PubMed:24891338). Plays a role in eye development (PubMed:24891338)

Subcellular Localization：Basolateral cell membrane

Expression：
Tissue_Specificity: Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney

Isoforms & Post-Translational Modification：Q6ZMH5: 540 amino acids, molecular weight 56461 Da.

Subunit：Homodimer

Synonyms

LZT-Hs7; MYP24; ZIP5

각종 서류

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/molm-14-cell.html [Content Brief]