SLC44A4 Antibody (YA7065)
(Synonyms: C6orf29 antibody; Choline transporter-like protein 4 antibody; CTL4 antibody; CTL4_HUMAN antibody; NG22 antibody; Slc44a4 antibody; Solute carrier family 44 member 4 antibody; UNQ441/PRO874 antibody)SLC44A4 Antibody (YA7065) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to SLC44A4.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500 |
Product Details
SLC44A4 Antibody (YA7065) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to SLC44A4.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 79 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 79 kDa
Recombinant protein within human SLC44A4 aa 56-229/710.
Endogenous
Protein G affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SLC44A4 is a Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury. Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis |Also has thiamine pyrophosphate transporter activity[1][2][3][4].
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Subcellular Localization
Membrane,Apical cell membrane
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Expression
Tissue_Specificity: Highly expressed in colon, also detected in prostate, trachea and lung (PubMed:24379411). Isoform 3 is also expressed in colon but a lower levels (PubMed:24379411)|Expressed in colon at low levels -
Isoforms & Post-Translational Modification
Q53GD3 has four isomers: Q53GD3-1: 79254 Da (predicted); Q53GD3-2: 32729 Da (predicted); Q53GD3-3: 70762 Da (predicted); Q53GD3-4: 74504 Da (predicted).
N-glycosylated; N-glycosylation of Asn-69, Asn-155 and Asn-393 is required for a proper thiamine pyrophosphate uptake -
SwissProt ID
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Synonyms
C6orf29 antibody; Choline transporter-like protein 4 antibody; CTL4 antibody; CTL4_HUMAN antibody; NG22 antibody; Slc44a4 antibody; Solute carrier family 44 member 4 antibody; UNQ441/PRO874 antibody
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