SLC44A4 Antibody (YA7065)

Cat. No.: HY-P87382: Ficha de datos User Guide for Antibodies
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SLC44A4 Antibody (YA7065) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to SLC44A4.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

SLC44A4 Antibody (YA7065) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to SLC44A4.

Host

Mouse

Clonality

Monoclonal

Peso molecular

Predicted band size: 79 kDa;

Observed band size: 79 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q53GD3

Immunogen

Recombinant protein within human SLC44A4 aa 56-229/710.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500

Sensitivity	Endogenous	Pureza	Protein G affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity) (PubMed:23651124, PubMed:28013291). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (PubMed:24379411, PubMed:26741288)|Also has thiamine pyrophosphate transporter activity

Subcellular Localization：Membrane,Apical cell membrane

Expression：
Tissue_Specificity: Highly expressed in colon, also detected in prostate, trachea and lung (PubMed:24379411). Isoform 3 is also expressed in colon but a lower levels (PubMed:24379411)|Expressed in colon at low levels

Isoforms & Post-Translational Modification：Q53GD3 has four isomers: Q53GD3-1: 79254 Da (predicted); Q53GD3-2: 32729 Da (predicted); Q53GD3-3: 70762 Da (predicted); Q53GD3-4: 74504 Da (predicted).
N-glycosylated; N-glycosylation of Asn-69, Asn-155 and Asn-393 is required for a proper thiamine pyrophosphate uptake

Synonyms

C6orf29 antibody; Choline transporter-like protein 4 antibody; CTL4 antibody; CTL4_HUMAN antibody; NG22 antibody; Slc44a4 antibody; Solute carrier family 44 member 4 antibody; UNQ441/PRO874 antibody

Documentación

User Guide for Antibodies (1077 KB)