SOX10 Antibody (YA6775)

Cat. No.: HY-P87082: Ficha de datos User Guide for Antibodies
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SOX10 Antibody (YA6775) is a Rat -derived and non-conjugated monoclonal antibody, targeting to SOX10.

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño	Stock	Cantidad
20 μL	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

SOX10 Antibody (YA6775) is a Rat -derived and non-conjugated monoclonal antibody, targeting to SOX10.

Host

Rat

Clonality

Recombinant,Monoclonal

Peso molecular

Predicted band size: 50 kDa

Species Reactivity

Mouse, Rat Predicted Reactivity: Cynomolgus monkey,Pig

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.

SwissProt ID

P56693

Gene ID

6663 [NCBI]

Immunogen

Synthetic peptide within C terminal human SOX10.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-F IHC-F: Immunohistochemistry-Frozen	1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:1000
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:1000

Pureza	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity)

Subcellular Localization：Cytoplasm,Nucleus,Mitochondrion outer membrane

Expression：
Tissue_Specificity: Expressed in fetal brain and in adult brain, heart, small intestine and colon

Isoforms & Post-Translational Modification：P56693 has two isomers: P56693-1: 49911 Da (predicted); P56693-2: 31088 Da (predicted).

Subunit：Monomer

Synonyms

DOM antibody; DOM antibody; Dominant megacolon mouse human homolog of antibody; MGC15649 antibody; PCWH antibody; SOX 10 antibody; SOX10 antibody; SOX10_HUMAN antibody; SRY (sex determining region Y) box 10 antibody; SRY (sex determining region Y) box 10 antibody; DOM antibody; DOM antibody; Dominant megacolon mouse human homolog of antibody; MGC15649 antibody; PCWH antibody; SOX 10 antibody; SOX10 antibody; SOX10_HUMAN antibody; SRY (sex determining region Y) box 10 antibody; SRY (sex determining region Y) box 10 antibody; SRY box 10 antibody; SRY box containing gene 10 antibody; SRY related HMG box gene 10 antibody; SRY related HMG box gene 10 antibody; Transcription factor SOX 10 antibody; Transcription factor SOX-10 antibody; WS2E antibody; WS4 antibody; WS4C antibody;

Documentación

User Guide for Antibodies (1077 KB)