SV2A Antibody (YA6782)

Cat. No.: HY-P87089: Ficha de datos User Guide for Antibodies
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SV2A Antibody (YA6782) is a Rat -derived and non-conjugated IgG monoclonal antibody, targeting to SV2A.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

SV2A Antibody (YA6782) is a Rat -derived and non-conjugated IgG monoclonal antibody, targeting to SV2A.

Host

Rat

Clonality

Recombinant,Monoclonal

Peso molecular

Predicted band size: 83 kDa;

Observed band size: 83 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Mouse, Rat Predicted Reactivity: Cynomolgus monkey,Pig

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.

SwissProt ID

Q9JIS5

Gene ID

64051 [NCBI]

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-F IHC-F: Immunohistochemistry-Frozen	1:500
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:500 WB: 1:5000

Pureza	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles|(Microbial infection) Receptor for C.botulinum neurotoxin type A (BoNT/A, botA); the toxin probably binds via extracellular loop 4 (PubMed:16543415)|(Microbial infection) Possible receptor for C.botulinum neurotoxin type D (BoNT/D, botD); BoNT/D does not bind to extracellular loop 4 as do BoNT/A and BoNT/E (PubMed:21483489)|(Microbial infection) Receptor for C.botulinum neurotoxin type E (BoNT/E); the toxin probably binds via extracellular loop 4 (PubMed:18815274). It probably requires glycosylation of Asn-573 (PubMed:18815274)

Subcellular Localization：Presynapse,Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane

Expression：
Tissue_Specificity: Expressed in conventional synapses and cone ribbon synapses in the retina (at protein level) (PubMed:12687700). Expressed in diaphragm motor nerve terminals (at protein level) (PubMed:16543415). Expressed in hippocampus neurons (at protein level) (PubMed:18815274)

Subunit：Interacts with SYT1/synaptotagmin-1 in a calcium-dependent manner

Synonyms

KIAA0736 antibody; OTTHUMP00000014065 antibody; SV2 antibody; Sv2a antibody; SV2A_HUMAN antibody; Synaptic vesicle glycoprotein 2 antibody; Synaptic vesicle glycoprotein 2A antibody; Synaptic vesicle protein 2a antibody;

Documentación

User Guide for Antibodies (1077 KB)