Sv2a - synaptic vesicle glycoprotein 2 a Gene

Also Known as mKIAA0736

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64051

Summary

Enables protein kinase binding activity. Involved in synaptic vesicle priming. Acts upstream of or within cellular calcium ion homeostasis. Located in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and synaptic vesicle. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human SV2A (synaptic vesicle glycoprotein 2A). [provided by Alliance of Genome Resources, Apr 2022]

Sv2a Products (1)

mRNA Protein Name
NM_022030.3 NP_071313.1 synaptic vesicle glycoprotein 2A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein kinase binding IPI
IPI: Inferred from physical interaction
21307259 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within intracellular calcium ion homeostasis IDA
IDA: Inferred from direct assay
10624962 MGI
involved in synaptic vesicle priming IDA
IDA: Inferred from direct assay
19176798 MGI
involved in synaptic vesicle priming IMP
IMP: Inferred from mutant phenotype
19176798 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
19176798 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
19176798 MGI
located in cell-cell junction IDA
IDA: Inferred from direct assay
12074840 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
19176798 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
19176798 MGI
located in neuromuscular junction IDA
IDA: Inferred from direct assay
15713258 MGI
is active in neuron projection IDA
IDA: Inferred from direct assay
21664258 MGI
is active in presynaptic active zone IDA
IDA: Inferred from direct assay
21664258 MGI
located in presynaptic active zone IDA
IDA: Inferred from direct assay
24035762 MGI
located in synaptic vesicle IDA
IDA: Inferred from direct assay
10624962 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptic vesicle glycoprotein 2A

  • calcium regulator SV2A

  • synaptic vesicle protein 2

  • synaptic vesicle protein 2A

Sv2a Antibodies

Cat. No. Product Name Application Reactivity
HY-P87089 SV2A Antibody (YA6782) IHC-F, IHC-P, WB Mouse, Rat

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0106 Levetiracetam Inhibitor 99.98% Unkown

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-119810 Seletracetam Modulator 99.70% Phase 3
HY-136873 UCB-J Ligand 99.62% Phase 2
HY-157999 SDI-118 Modulator 98.86% Phase 1

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-167830 SDM-8 99.79% Unkown
HY-180554 UCB1244283 Modulator / Unkown
HY-119810B Seletracetam lithium bromide Modulator / Unkown
HY-136873A (Rac)-UCB-J Ligand / Unkown
HY-176866 Rodin-A Inhibitor / Unkown
HY-176867 Rodin-B Inhibitor / Unkown
HY-B0106S Levetiracetam-d6 Inhibitor / Unkown
HY-RS14054 SV2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-B0106S1 Levetiracetam-d3 Inhibitor / Unkown
HY-RS16880 Sv2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23322 Sv2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-119810A Seletracetam lithium / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sv2a NCBI NCBI:9900