TACC2 Antibody (YA8700)
(Synonyms: AZU-1; ECTACC)TACC2 Antibody (YA8700) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TACC2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
TACC2 Antibody (YA8700) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TACC2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
Human recombinant protein fragment corresponding to amino acids 727-1026 of human TACC2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TACC2 plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors. May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker
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Subcellular Localization
Cytoplasm,Nucleus,Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
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Expression
Tissue_Specificity: Strongly expressed in heart, skeletal muscle, brain, prostate, thyroid and trachea -
Isoforms & Post-Translational Modification
O95359 has 6 isomers: O95359-4: 309427 Da (predicted); O95359-1: 112111 Da (predicted); O95359-2: 64156 Da (predicted); O95359-3: 301058 Da (predicted); O95359-5: 119359 Da (predicted); O95359-6: 108690 Da (predicted).
Phosphorylated by TTK; which is required for localization in centrosome -
Subunit
Interacts with CCDC100/CEP120 (By similarity)
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SwissProt ID
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Synonyms
AZU-1; ECTACC
Documentation
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