Talin 1 Antibody
(Synonyms: ILWEQ, Talin 1, Talin, Talin-1, TLN 1, TLN, Tln1, TLN1_HUMAN)Talin 1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Talin 1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:50-100 |
Product Details
Talin 1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Talin 1.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse
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Calculated Molecular Weight Predicted band size: 270 kDa;
Synthetic peptide of human Talin 1.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Talin 1 is a High molecular weight cytoskeletal protein concentrated at regions of cell-matrix and cell-cell contacts. Involved in connections of major cytoskeletal structures to the plasma membrane. With KANK1 co-organize the assembly of cortical microtubule stabilizing complexes (CMSCs) positioned to control microtubule-actin crosstalk at focal adhesions (FAs) rims
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Subcellular Localization
Cell projection, ruffle membrane; Cytoplasm, cytoskeleton; Cell surface; Cell junction, focal adhesion
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Expression
Tissue_Specificity: Expressed at low to non-detectable levels in many tissues but highly expressed in skin and pancreas with other tissues including kidney cortex, endocervix, testis, pituitary, liver, and spleen also showing robust expression.
Induction: By a combination of TGFB and EGF. -
Isoforms & Post-Translational Modification
Talin 1 has 2 isoforms, Q9Y490-1: amino acid length is 2541, molecular weight is 269767 Da (predicted); Q9Y490-2: amino acid length is 2558, molecular weight is 271420 Da (predicted).
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Subunit
Part of a complex composed of THSD1, PTK2/FAK1, TLN1 and VCL.
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SwissProt ID
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Synonyms
ILWEQ, Talin 1, Talin, Talin-1, TLN 1, TLN, Tln1, TLN1_HUMAN
Documentation
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