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Cat. No.: HY-P87628

Tenascin Antibody (YA7312)

Tenascin Antibody (YA7312) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tenascin.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	IHC-F IHC-F: Immunohistochemistry-Frozen	IF-Tissue IF-Tissue: Immunofluorescence-Tissue
Dilution Ratio	1:100-500	1:100-500	1:100-500

Description

Tenascin Antibody (YA7312) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tenascin.

Host Rabbit
Clonality Recombinant,Monoclonal
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 241 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 241 kDa

Immunogen

A synthesized peptide derived from human Tenascin

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

Tenascin is an Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells^[1].
Subcellular Localization

Secreted, extracellular space, extracellular matrix
Expression

Tissue_Specificity: Detected in fibroblasts (at protein level)
Isoforms & Post-Translational Modification

P24821 has 6 isomers: P24821-1: 240853 Da (predicted); P24821-2: 191373 Da (predicted); P24821-3: 201359 Da (predicted); P24821-4: 230867 Da (predicted); P24821-5: 181528 Da (predicted); P24821-6: 171360 Da (predicted).
Subunit

Homohexamer; disulfide-linked
SwissProt ID

P24821