TGF alpha Antibody (YA037)(PBS only)

Cat. No.: HY-P80911A: Data Sheet User Guide for Antibodies
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TGF alpha Antibody (YA037) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TGF alpha.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

TGF alpha Antibody (YA037) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TGF alpha.

Host

Rabbit

분자량

Predicted band size: 17 kDa;

Observed band size: 17 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P01135

Gene ID

7039 [NCBI]

Immunogen

Synthetic peptide corresponding to Human TGF alpha.The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IP IP: Immunoprecipitation	1:20

Purity	affinity purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar

Subcellular Localization：Secreted, extracellular space; Cell membrane; Single-pass type I membrane protein

Expression：
Tissue_specificity:Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines

Isoforms & Post-Translational Modification：P01135 has 5 isomers: P01135-1: 17006 Da (predicted); P01135-2: 16935 Da (predicted); P01135-3: 17079 Da (predicted); P01135-4: 17400 Da (predicted); P01135-5: 17329 Da (predicted).

Subunit：Interacts with the PDZ domains of MAGI3, SDCBP and SNTA1. The interaction with SDCBP, is required for the targeting to the cell surface. In the endoplasmic reticulum, in its immature form (i.e. with a prosegment and lacking full N-glycosylation), interacts with CNIH. In the Golgi apparatus, may form a complex with CNIH and GORASP2. Interacts (via cytoplasmic C-terminal domain) with NKD2

Research Field

Cardiovascular

Synonyms

ETGF; TFGA; TGF A; TGF-alpha; Tgfa; Wa1; Waved 1

각종 서류

User Guide for Antibodies (1077 KB)