TGF alpha Antibody (YA037)(PBS only)
(Synonyms: ETGF; TFGA; TGF A; TGF-alpha; Tgfa; Wa1; Waved 1)TGF alpha Antibody (YA037) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TGF alpha.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IP
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IP
IP: Immunoprecipitation
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|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 | 1:20 |
Product Details
TGF alpha Antibody (YA037) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TGF alpha.
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Host Rabbit
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 17 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 17 kDa
Synthetic peptide corresponding to Human TGF alpha.The exact sequence is proprietary to MCE.
affinity purified
Non-conjugated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Transforming growth factor α (TGF-alpha; TGF-α) is a mitogenic polypeptide member of the epidermal growth factor (EGF) family of cytokines. TGF-α is composed of 50 amino acids, and displays 35-40% homology with EGF which is the prototypic member of the EG
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Subcellular Localization
Secreted, extracellular space; Cell membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines -
Isoforms & Post-Translational Modification
P01135 has 5 isomers: P01135-1: 17006 Da (predicted); P01135-2: 16935 Da (predicted); P01135-3: 17079 Da (predicted); P01135-4: 17400 Da (predicted); P01135-5: 17329 Da (predicted).
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Subunit
Interacts with the PDZ domains of MAGI3, SDCBP and SNTA1. The interaction with SDCBP, is required for the targeting to the cell surface. In the endoplasmic reticulum, in its immature form (i.e. with a prosegment and lacking full N-glycosylation), interacts with CNIH. In the Golgi apparatus, may form a complex with CNIH and GORASP2. Interacts (via cytoplasmic C-terminal domain) with NKD2
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SwissProt ID
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Synonyms
ETGF; TFGA; TGF A; TGF-alpha; Tgfa; Wa1; Waved 1
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Research Field
Cardiovascular
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