Tissue Factor Antibody (YA2471)(PBS only)

Cat. No.: HY-P82726A: Data Sheet User Guide for Antibodies
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Tissue Factor Antibody (YA2471) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tissue Factor.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Tissue Factor Antibody (YA2471) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tissue Factor.

Host

Rabbit

Molecular Weight

Predicted band size: 33 kDa;

Observed band size: 45 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P13726

Gene ID

2152 [NCBI]

Immunogen

A synthetic peptide of human Tissue Factor

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade

Subcellular Localization：Membrane; Single-pass type I membrane protein; Secreted

Expression：
Tissue_specificity:Lungs, placenta and pancreas

Induction:TF expression is highly dependent upon cell type. TF can also be induced by the inflammatory mediators interleukin 1 and TNF-alpha, as well as by endotoxin, to appear on monocytes and vascular endothelial cells as a component of cellular immune response

Isoforms & Post-Translational Modification：P13726 has 2 isomers: P13726-1: 33068 Da (predicted); P13726-2: 27145 Da (predicted).

Subunit：Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII

Research Field

Cardiovascular

Synonyms

F3; Tissue factor; TF; Coagulation factor III; Thromboplastin; CD antigen CD142

Documentation

User Guide for Antibodies (1077 KB)