F3 - coagulation factor III, tissue factor Gene

Also Known as TF; TFA; CD142

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 2152

About F3

Cytogenetic location: 1p21.3 Genomic coordinates (GRCh38): 1:94,529,173-94,541,759 (from NCBI)

This gene has 4 transcripts (splice variants), 246 orthologues and 11 paralogues. Ubiquitous expression in placenta (RPKM 54.0), gall bladder (RPKM 41.2) and 22 other tissues.

Summary

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the Other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces, for example, on monocytes. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. Platelets and monocytes have been shown to express this coagulation factor under procoagulatory and proinflammatory stimuli, and a major role in HIV-associated coagulopathy has been described. Platelet-dependent monocyte expression of coagulation factor III has been described to be associated with Coronavirus Disease 2019 (COVID-19) severity and mortality. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Aug 2020]

F3 Products (2)

mRNA	Protein	Name
NM_001178096.2	NP_001171567.1	tissue factor isoform 2 precursor
NM_001993.5	NP_001984.1	tissue factor isoform 1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables phospholipid binding	IDA IDA: Inferred from direct assay	17469850	GOA
enables protease binding	IPI IPI: Inferred from physical interaction	3455766	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	8598903	GOA
contributes to serine-type endopeptidase activity	IDA IDA: Inferred from direct assay	24998411	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in activation of cysteine-type endopeptidase activity involved in apoptotic process	IDA IDA: Inferred from direct assay	17898544	GOA
involved in activation of plasma proteins involved in acute inflammatory response	IDA IDA: Inferred from direct assay	17469850	GOA
involved in blood coagulation	IDA IDA: Inferred from direct assay	8632006	GOA
involved in positive regulation of TOR signaling	IMP IMP: Inferred from mutant phenotype	18612547	GOA
involved in positive regulation of angiogenesis	IDA IDA: Inferred from direct assay	17898544	GOA
involved in positive regulation of endothelial cell proliferation	IDA IDA: Inferred from direct assay	17898544	GOA
acts upstream of or within positive regulation of gene expression	IMP IMP: Inferred from mutant phenotype	22556343	GOA
acts upstream of or within positive regulation of interleukin-8 production	IMP IMP: Inferred from mutant phenotype	22556343	GOA
involved in positive regulation of platelet-derived growth factor receptor signaling pathway	IDA IDA: Inferred from direct assay	17991872	GOA
involved in protein processing	IDA IDA: Inferred from direct assay	24998411	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in cell surface	IDA IDA: Inferred from direct assay	17898544	GOA
located in collagen-containing extracellular matrix	IDA IDA: Inferred from direct assay	2704749	GOA
located in extracellular space	IDA IDA: Inferred from direct assay	19065458	GOA
part of serine-type peptidase complex	IPI IPI: Inferred from physical interaction	24998411	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

F3 Protein Structure

Tissue_fac

Interfer-bind

0
100
200
295 a.a.

Protein Preferred Names	Protein Names
tissue factor	coagulation factor III (thromboplastin, tissue factor)

F3 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	F3	P13726	F7	Homo sapiens	P08709	PLA	25241761
Intra	F3	P13726	F7	Homo sapiens	P08709	ELISA	8940045
Intra	F3	P13726	F2RL1	Homo sapiens	P55085	Anti Bait CoIP	16959886
Intra	F3	P13726	TM9SF4	Homo sapiens	Q92544	Anti Tag CoIP	33961781
Intra	F3	P13726	TM9SF4	Homo sapiens	Q92544	Anti Tag CoIP	28514442
Intra	F3	P13726	HPCAL4	Homo sapiens	Q9UM19	Validated Y2H	32296183
Intra	F3	P13726	HPCAL4	Homo sapiens	Q9UM19	Y2H Array	32296183
Intra	F3	P13726	HPCAL4	Homo sapiens	Q9UM19	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant F3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7787	Coagulation factor III/F3 Protein, Human (HEK293, His)	P13726-1 (G34-E251)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P7787A	Coagulation factor III/F3 Protein, Human (HEK293, Fc)	P13726-1 (S33-E251)	≥ 95%, as determined by reducing SDS-PAGE.

F3 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P82726	Tissue Factor Antibody (YA2471)	WB, IHC-P	Human, Mouse, Rat
HY-P82726A	Tissue Factor Antibody (YA2471)(PBS only)	WB, IHC-P	Human, Mouse, Rat
HY-P84965	Tissue Factor Antibody (YA7080)

Related Diseases

Diseases	Alias
Disseminated Intravascular Coagulation	Defibrination Syndrome Dic Diffuse Or Disseminated Intravascular Coagulation Fibrinolytic Purpura Consumption Coagulopathy Diffuse Intravascular Coagulation Dic - [Disseminated Intravascular Coagulation] Disseminated Intravascular Coagulopathy Fibrinolysis Nos Thrombolytic Purpura
Carotid Artery Thrombosis
Factor Vii Deficiency	Hypoproconvertinemia F7 Deficiency Congenital Proconvertin Deficiency Congenital Factor Vii Deficiency Factor 7 Deficiency Deficiency, Stable Proconvertin Deficiency Prothrombin Conversion Accelerator Deficiency Serum Prothrombin Conversion Accelerator Deficiency Proconvertin Deficiency, Congenital FA7D Stable Disease Deficiency, Factor Vii
Antiphospholipid Syndrome	Antiphospholipid Antibody Syndrome Hughes Syndrome Familial Antiphospholipid Syndrome Aps Lupus Anticoagulant, Familial Anti-Phospholipid Syndrome Apls Classic Apls Classic Antiphospholipid Syndrome Acromegaloid Facial Appearance Syndrome Anticardiolipin Syndrome
Hemorrhagic Disease	Hemorrhagic Disorders Hemorrhagic Diathesis Hemorrhagic Diseases Bleeding Tendency Acquired Coagulation Factor Inhibitor Disorder Acquired Inhibitor Of Coagulation Antithrombinaemia Antithromboplastinogenaemia Circulating Anticoagulant Disorder Haemorrhagic Disorder Due To Antithrombinaemia Haemorrhagic Disorder Due To Excess Administered Heparin Antithromboplastinaemia Haemorrhagic Disorder Due To Hyperheparinemia
Factor Xii Deficiency	Hageman Factor Deficiency Haf Deficiency Factor Xii Deficiency Disease F12 Deficiency Deficiency, Hageman Coagulation Factor 12 Deficiency Factor 12 Deficiency Congenital Factor Xii Deficiency Congenital Hageman Factor Deficiency FA12D Factor Xii Deficiency, Factor Xii
Von Willebrand'S Disease	Von Willebrand Disease Von Willebrand Disorder Vascular Pseudohemophilia Hereditary Von Willebrand Disease Vwd Vascular Hemophilia Von Willebrand'S-Jurgens' Disease Von Willebrand-Jrgens Disease Von Willebrand Factor Deficiency Von Willebrand Factor, Deficiency Angiohemophilia Von Willebrand'S Factor Deficiency Von Willebrand Diseases Factor Viii Deficiency With Vascular Defect Vascular Haemophilia Willebrand Jurgen Thrombopathy Pseudohaemophilia Minot-Von Willebrand-Jurgen Disease Angiohaemophilia Angiohaemophilia A Angiohaemophilia B
Heparin-Induced Thrombocytopenia	Hit Hat Heparin-Associated Thrombocytopenia Heparin-Induced Thrombocytopenia Type 2
Covid-19	2019 Novel Coronavirus 2019-Ncov Infection Covid19 Sars-Cov-2 Infection Wuhan Coronavirus Infection Wuhan Seafood Market Pneumonia Virus Infection
Factor Xi Deficiency	Plasma Thromboplastin Antecedent Deficiency Rosenthal Syndrome Pta Deficiency Hemophilia C Rosenthal Factor Deficiency F11 Deficiency Congenital Factor Xi Deficiency Hereditary Factor Xi Deficiency Disease Haemophilia C Factor Xi Deficiency, Autosomal Dominant Rosenthal'S Disease Factor 11 Deficiency Factor Xi Factor Xi Deficiency, Autosomal Recessive Factor Xi Deficiency, Congenital FA11D Thromboplastin Antecedent Deficiency Pta - [Plasma Thromboplastin Antecedent] Deficiency Congenital Factor Xi Deficiency Disease Rosenthal Disease
Pulmonary Embolism	Pulmonary Artery Embolism Pulmonary Embolus Pulmonary Emboli
Hemophilia B	Christmas Disease Factor Ix Deficiency F9 Deficiency HEMB Plasma Thromboplastin Component Deficiency Congenital Factor Ix Deficiency Mild Hemophilia B Severe Hemophilia B Congenital Factor Ix Disorder Deficiency, Functional Factor Ix Hem B Mild Congenital F9 Deficiency Mild Congenital Factor Ix Deficiency Moderate Hemophilia B Moderate Congenital F9 Deficiency Moderate Congenital Factor Ix Deficiency Severe Congenital F9 Deficiency Severe Congenital Factor Ix Deficiency Bleeding Disorder In Hemophilia B Carriers Congenital F9 Deficiency Recessive X-Linked Hemophilia B
Hantavirus Pulmonary Syndrome	Hps Four Corners Hantavirus Hards Hantavirus Hantavirus-Associated Respiratory Distress Syndrome Hanta Virus Hantavirus Cardiopulmonary Syndrome Hps - [Hantavirus Pulmonary Syndrome] Hcps - [Hantavirus Cardiopulmonary Syndrome]
Factor V Deficiency	Parahemophilia Labile Factor Deficiency Proaccelerin Deficiency Owren Disease Owren Parahemophilia Quebec Platelet Disorder Deficiency, Labile Hereditary Hypoproaccelerinaemia Owren'S Disease Congenital Factor V Deficiency FA5D Factor 5 Deficiency Deficiency, Factor V
Intracranial Hypertension	Raised Intracranial Pressure
Factor X Deficiency	Stuart-Prower Factor Deficiency F10 Deficiency Congenital Stuart Factor Deficiency Factor X Deficiency, Congenital Congenital Factor X Deficiency Disease, Stuart-Prower Stuart Factor Deficiency, Congenital FA10D Factor 10 Deficiency Deficiency, Factor X Hereditary Factor X Deficiency Disease Deficiency Of Factor X Stuart Deficiency Disease Stuart Prower Deficiency Stuart-Prower Disease
Thrombophilia Due To Activated Protein C Resistance	Activated Protein C Resistance Apc Resistance THPH2 Thrombophilia Due To Deficiency Of Activated Protein C Cofactor Proc Cofactor Deficiency Pccf Deficiency Thrombophilia V Thrombophilia, Susceptibility To, Due To Factor V Leiden Thrombophilia Due To Factor V Leiden Thrombophilia 2 Due To Activated Protein C Resistance Thrombophilia, Susceptibility To, Due To Activated Protein C Resistance
Pulmonary Artery Disease	Abnormality Of The Pulmonary Artery
Afibrinogenemia, Congenital	Congenital Afibrinogenemia Afibrinogenemia Factor I Deficiency Familial Afibrinogenemia Hypofibrinogenemia, Congenital Fibrinogen Deficiency Afibrinogenemia Congenital CAFBN Congenital Hypofibrinogenemia Hypofibrinogenemia Complement Factor I Deficiency
Thrombotic Thrombocytopenic Purpura	Purpura, Thrombotic Thrombocytopenic Ttp Thrombotic Thrombocytopenic Purpura, Acquired Idiopathic Thrombotic Thrombocytopenic Purpura Moschcowitz Disease Moschcowitz'S Syndrome Moschowitz Syndrome Chronic Relapsing Thrombotic Thrombocytopenic Purpura Familial Thrombotic Thrombocytopenia Purpura Moschkowitz Disease Purpura Thrombotic Thrombocytopenic Familial Thrombotic Thrombocytopenic Purpura Microangiopathic Hemolytic Anemia Congenital Thrombotic Thrombocytopenic Purpura Autoimmune Thrombotic Thrombocytopenic Purpura Ttp - [Thrombotic Thrombocytopenic Purpura] Moschcowitz Syndrome
Protein S Deficiency	Protein S Deficiency Disease Hereditary Thrombophilia Due To Protein S Deficiency
Thrombophilia	Hypercoagulability State
Sagittal Sinus Thrombosis	Thrombosis Of Superior Longitudinal Sinus Thrombosis Of Superior Sagittal Sinus Thrombosis Superior Sagittal Sinus
Thrombosis	Thrombosis Of Blood Vessel
Liver Disease	Liver Failure Liver Diseases Abnormality Of The Liver Liver Dysfunction Disorder Of Liver Hepatic Disorder Hepatic Disease Disease Of Bilirubin Metabolism Disorder Of Bilirubin Metabolism Liver Decompensation Liver Function Failure Hepatic Failure Nos Liver Failure Nos End Stage Liver Disease Decompensated Liver Failure Decompensation Of Liver Function Hepatic Decompensation Hepatic Insufficiency Liver Cell Necrosis With Hepatic Failure Liver Insufficiency Decompensated Liver Disease End Stage Liver Failure Liver Necrosis With Hepatic Failure
Nonbacterial Thrombotic Endocarditis	Non-Bacterial Thrombotic Endocarditis Marantic Endocarditis Non-Infective Endocarditis
Hemophilia A	Factor Viii Deficiency Haemophilia A Mild Hemophilia A HEMA Hemophilia, Classic Classic Hemophilia Factor 8 Deficiency Severe Hemophilia A Classical Hemophilia Hem A Hemophilia A, Congenital Mild Congenital F8 Deficiency Mild Congenital Factor Viii Deficiency Severe Congenital F8 Deficiency Severe Congenital Factor Viii Deficiency Moderate Hemophilia A Moderate Congenital F8 Deficiency Moderate Congenital Factor Viii Deficiency Bleeding Disorder In Hemophilia A Carriers Congenital F8 Deficiency Congenital Fviii Deficiency Congenital Factor Viii Deficiency Mild Hereditary Factor Viii Deficiency Disease Severe Hereditary Factor Viii Deficiency Disease Ahg - [Antihaemophilic Globulin] Deficiency Ahg - [Antihaemophilic Globulin] Deficiency Disease Congenital Factor Viii Disorder Sex-Linked Factor Viii Deficiency Antihaemophilic Globulin Deficiency Classic Haemophilia Familial Haemophilia Haemophilia Hereditary Haemophilia Subhaemophilia Haemophilia Nos
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Scrub Typhus	Tsutsugamushi Disease Tsutsugamushi Fever Typhus Fever Due To Rickettsia Tsutsugamushi Chigger-Borne Rickettsiosis Chigger-Borne Typhus Japanese River Fever Kedani Fever Mite-Borne Rickettsiosis Mite-Borne Typhus Scrub Typhus Scrub Mite-Borne Typhus Tropical Typhus Tsutsugamushi
Intracranial Thrombosis	Cerebral Thrombosis Thrombosis Of Cerebral Veins Cerebral Arterial Thrombosis
Thrombophilia Due To Thrombin Defect	Venous Thromboembolism Venous Thrombosis Thrombophilia Due To Factor 2 Defect Thromboembolism THPH1 Thromboembolism, Susceptibility To Venous Thromboembolism, Susceptibility To Venous Thrombosis, Protection Against Prothrombin-Related Thrombophilia Hyperprothrombinemia Venous Thrombosis, Susceptibility To Thrombophilia 1 Due To Thrombin Defect F2-Related Thrombophilia Factor Ii-Related Thrombophilia Prothrombin 20210g>A Thrombophilia Prothrombin G20210a Thrombophilia Prothrombin Thrombophilia
Thrombocytosis	Thrombocythaemia
Blood Platelet Disease	Platelet Disorder Blood Platelet Disorders Thrombocytopathy Platelet Dysfunction Platelet Disorders Qualitative Platelet Deficiency
Hepatic Veno-Occlusive Disease	Veno-Occlusive Disease Sinusoidal Obstruction Syndrome Hepatic Venoocclusive Disease Venoocclusive Disease Hepatic Vein Thrombosis Budd-Chiari Syndrome Hepatic Vein Occlusion Veno-Occlusive Disease Of The Liver
Purpura Fulminans	Purpura Gangrenosa
Acute Myocardial Infarction	Cardiac Attack Heart Attack
Purpura	Purpuric Disorder
Prothrombin Deficiency	Factor Ii Deficiency Hypoprothrombinemia Dysprothrombinemia Deficiency, Prothrombin Inherited Factor Ii Deficiency Hereditary Factor Ii Deficiency Disease
Blood Coagulation Disease	Blood Coagulation Disorders Coagulation Protein Disease Inherited Blood Coagulation Disease Postpartum Coagulation Defect Postpartum Coagulation Defect With Delivery Coagulation Protein Disorders Puerperal Coagulopathy
Coronary Thrombosis	Coronary Artery Thrombosis
Budd-Chiari Syndrome	Hepatic Vein Thrombosis Chiari Syndrome BDCHS Membranous Obstruction Of The Inferior Vena Cava Budd-Chiari Syndrome, Somatic Movc Budd-Chiari Syndrome, Susceptibility To, Somatic Budd-Chiari Syndrome, Susceptibility To Membranous Obstruction Of Inferior Vena Cava Hepatic Vein Block Obstruction Of Hepatic Veins Hepatic Vein Obstruction Hepatic Venous Block
Factor Xiii Deficiency	Hereditary Factor Xiii Deficiency Disease Deficiency, Laki-Lorand Factor Congenital Factor Xiii Deficiency Fibrin Stabilizing Factor Deficiency Deficiency, Factor Xiii Factor Xiii Deficiency Disease Deficiency Of Factor Xiii Fibrin-Stabilizing Factor Deficiency Factor Xiii Deficiency, Congenital
Glanzmann Thrombasthenia 1	Glanzmann Thrombasthenia Thrombasthenia Of Glanzmann And Naegeli Glanzmann'S Thrombasthenia Bdplt2 Platelet Glycoprotein Iib-Iiia Deficiency Deficiency Of Platelet Fibrinogen Receptor GT1 Gt Platelet Fibrinogen Receptor Deficiency Glycoprotein Complex Iib-Iiia Deficiency Deficiency Of Glycoprotein Complex Iib-Iiia Glycoprotein Iib/Iiia Defect Glanzmann Thrombasthenia, Type A Thrombasthenia Bleeding Disorder, Platelet-Type, 2 Gp Iib-Iiia Complex Deficiency Deficiency Of Gp Iib-Iiia Complex Platelet-Type Bleeding Disorder 2 Thrombocytasthenia Deficiency Of Gp 2b 3a Complex Diacyclothrombopathia 2b 3a Glanzmann Thrombasthenia Type A Platelet Fibrinogen Receptor, Deficiency Of Platelet Glycoprotein 2b 3a Deficiency Glanzmann Disease Glanzmann-Naegeli Disorder Hereditary Hemorrhagic Thrombasthenia Hereditary Thrombasthenia Bleeding Disorder Platelet-Type 2
Achenbach Syndrome	Paroxysmal Hematoma Of The Finger
Hemolytic-Uremic Syndrome	Hemolytic Uremic Syndrome Haemolytic-Uraemic Syndrome Hus Acute Renal Failure, Thrombocytopenia, And Microangiopathic Hemolytic Anemia Associated With Distorted Erythrocytes Typical Haemolytic Uraemic Syndrome Gasser Syndrome Hus - [Haemolytic Uraemic Syndrome]
Qualitative Platelet Defect	Qualitative Platelet Defects Qualitative Platelet Deficiency Thrombocytopathy Platelet Defect Platelet Disorder Thrombopathy Platelet Granule Defect Thrombocytasthenia Thromboasthenia Dystrophic Thrombocytopathy Haemorrhagic Thrombasthenia Granulopenic Thrombocytopathy
Stroke, Ischemic	Cerebral Infarction Stroke Ischemic Stroke Cerebrovascular Accident Cerebral Infarction, Susceptibility To Stroke, Ischemic, Susceptibility To Cerebral Infarct Ischemic Stroke, Susceptibility To Stroke, Susceptibility To Cva - Cerebral Infarction ISCHSTR Ischemic Cerebrovascular Accident
Chronic Urticaria	Urticaria Chronic Chronic Spontaneous Urticaria Chronic Ordinary Urticaria
Pyoderma
Femoral Neuropathy	Femoral Nerve Dysfunction Femoral Nerve Lesions
Monocytic Leukemia	Monocytic Leukaemia Schilling'S Leukaemia Schilling'S Leukemia M5b Acute Differentiated Monocytic Leukemia
Placental Insufficiency	Uteroplacental Vascular Insufficiency
Compartment Syndrome	Compartment Syndromes Compartmental Syndrome
Intracranial Embolism	Cerebral Embolism Cerebral Embolism With Cerebral Infarction
Vascular Disease	Vascular Diseases Aneurysm Spinal Cord Ischemia Vascular Anomaly Spinal Cord Vascular Diseases Vascular Tissue Disease
Retinal Vein Occlusion	Occlusion, Of Retinal Vein
Hepatitis A	Viral Hepatitis A Viral Hepatitis, Type A
Buruli Ulcer	Buruli Ulcer, Susceptibility To Buruli Ulcer Disease Mycobacterium Ulcerans Mycobacterium Ulcerans, Susceptibility To Bairnsdale Ulcer Daintree Ulcer Mossman Ulcer Searl Ulcer Searle'S Ulcer Bud
Pyoderma Gangrenosum	Phagedenic Pyoderma Phagedena Geometric
Angina Pectoris	Prinzmetal'S Variant Angina Angina Prinzmetal Angina Variant Angina Angina Inversa Prinzmetal'S Angina Coronary Artery Vasospasm Angina Pectoris, Variant Variant Angina Pectoris Vasospastic Angina Angor Pectoris Anginal Syndrome Ischaemic Chest Pain Angina Pectoris Syndrome Angina Syndrome Cardiac Angina Syndrome Ap - [Angina Pectoris] Angina Nos Ap - [Angina Pectoris] Syndrome Ischaemic Heart Disease With Angina Heart Angina Chest Angina Angina Attack Anginal Cardiopathy Coronary Pain Nos
Myocardial Infarction	Heart Attack Myocardial Infarction, Susceptibility To Myocardial Infarction 1 Myocardial Infarction, Protection Against Myocardial Infarction, Decreased Susceptibility To Myocardial Infarction, Decreased Myocardial Infarct MCI1 Premature Myocardial Infarction Myocardial Infarction, Susceptibility To, Type 1
Acquired Von Willebrand Syndrome	Acquired Von Willebrand Disease Willebrand Disease, Acquired Avws
Hemopneumothorax	Haemopneumothorax
Hellp Syndrome	Hemolysis, Elevated Liver Enzymes, Lowered Platelets Hemolysis, Elevated Liver Enzymes, Low Platelets In Pregnancy Hemolysis-Elevated Liver Enzymes-Low Platelets Syndrome Hellp - [Syndrome Of Haemolysis, Elevated Liver Enzymes And Low Platelet] Haemolysis-Elevated Liver Enzymes-Low Platelet Count Syndrome
Acute Cor Pulmonale
Acute Promyelocytic Leukemia	Leukemia, Acute Promyelocytic Acute Myeloblastic Leukemia Type 3 Aml M3 APL Leukemia, Acute Promyelocytic, Somatic Aml With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Apml Acute Myeloblastic Leukemia 3 Acute Myeloid Leukemia With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Acute Myeloblastic Leukaemia Type 3 Acute Myeloid Leukaemia M3 Acute Myeloid Leukemia M3 Acute Promyelocytic Leukaemia M3 Anll Myeloid Leukemia, Acute, M3 Leukemia Promyelocytic Acute Leukemia, Promyelocytic, Acute Leukemia, Acute, Promyelocytic
Crimean-Congo Hemorrhagic Fever	Crimean Hemorrhagic Fever Cchf Congo Hemorrhagic Fever Hemorrhagic Fever, Crimean Chf Congo Virus Congo-Crimean Hemorrhagic Fever Congo Fever Hemorrhagic Fever Crimean-Congo Cchf - [Crimean-Congo Haemorrhagic Fever] Kara Mikh Typhoid Fever Xīnjiāng Haemorrhagic Fever
Intracranial Sinus Thrombosis	Sinus Thrombosis, Intracranial
Giant Hemangioma
Hemopericardium	Haemopericardium Pericardial Effusion Haematopericardium Pneumohemopericardium Pericardium Haemorrhage Haemorrhagic Pericarditis
Erythema Multiforme	Dermatostomatitis, Erythema Multiforme Type Em Erythema Multiforme Bullosum Erythema Polymorphe, Erythema Multiforme Type Febrile Mucocutaneous Syndrome Herpes Iris, Erythema Multiforme Type Stevens-Johnson Syndrome Em - [Erythema Multiforme]
Liver Cirrhosis	Cirrhosis Cirrhosis Of Liver CIRRH Cryptogenic Cirrhosis Cirrhosis, Cryptogenic Cirrhosis Nos
Vein Disease	Disorder Of Vein
Cavernous Sinus Thrombosis	Thrombosis Of Cavernous Venous Sinus
Placenta Disease	Placenta Diseases Placenta Disorder Pregnancy Complications Placenta Disorders
Factor Viii Deficiency	Autosomal Hemophilia A Hemophilia A Autosomal Factor Viii Deficiency Classic Hemophilia A Congenital Factor Viii Disorder Subhemophilia Factor 8 Deficiency, Congenital Factor Viii
Hemolytic Anemia	Anemia, Hemolytic Anemia Hemolytic Anaemia Due To Other Disorders Of Glutathione Metabolism Chronic Non Spherocytic Anaemia G6pd - [Glucose-6-Phosphate Dehydrogenase Deficiency] Anaemia Anaemia Due To Glucose-6-Phosphate Dehydrogenase Deficiency Glucose-6-Phosphate Dehydrogenase Deficiency With Anaemia Glucose-6-Phosphate Dehydrogenase Deficiency Anaemia Favism Anaemia Haemolytic Anaemia Due Tog6pd Deficiency Favism Pentose Phosphate Pathway Disorder Anaemia Anaemia Due To Pentose Phosphate Pathway Defect
Post-Thrombotic Syndrome	Postphlebitic Syndrome Postthrombotic Syndrome Postphlebetic Syndrome With Inflammation Postphlebetic Syndrome With Ulcer Postphlebetic Syndrome With Ulcer And Inflammation Venous Stress Disorder
Pre-Eclampsia	Preeclampsia Gestational Hypertension Hypertension Induced By Pregnancy Pre-Eclamptic Toxaemia Pregnancy Associated Hypertension Proteinuric Hypertension Of Pregnancy Hypertension, Pregnancy-Induced, Susceptibility To Preeclampsia/Eclampsia Pregnancy Toxemia Toxaemia Of Pregnancy Gestational Proteinuric Hypertension Pregnancy-Induced Hypertension Toxemia Of Pregnancy Preeclampsia, Susceptibility To Transient Hypertension Of Pregnancy Gestational [Pregnancy-Induced] Hypertension Without Significant Proteinuria Gestational Hypertension Nos Mild Proteinuric Hypertension Of Pregnancy Pih - [Pregnancy-Induced Hypertension] Pregnancy-Induced Hypertension Nos Gestational [Pregnancy-Induced] Hypertension With Significant Proteinuria Pe - [Pre-Eclampsia] Pre-Eclampsia Nos Pre-Eclamptic Nos Pregnancy Pre-Eclampsia Puerperal Pre-Eclampsia Pre-Eclampsia Toxaemia Toxaemia In Pregnancy Pet - [Pre-Eclamptic Toxaemia] Maternal Toxaemia
Waterhouse-Friderichsen Syndrome	Fatal Pneumococcal Waterhouse-Friderichsen Syndrome Meningococcal Hemorrhagic Adrenalitis Waterhouse-Friderichsen Syndrome, Meningococcal Meningococcal Haemorrhagic Adrenalitis Meningococcal Adrenal Syndrome Acute Adrenal Insufficiency With Meningococcal Septicaemia Adrenal Haemorrhage Syndrome Waterhouse-Friderichsen Disease Meningococcal Waterhouse-Friderichsen Syndrome Haemorrhagic Meningococcal Adrenitis
Acute Pulmonary Heart Disease
Autoimmune Disease Of Cardiovascular System
Splenic Infarction	Splenic Infarct Splenic Infarcts Infarct Of The Spleen
Arteriosclerosis	Arteriosclerotic Vascular Disease
Subclavian Steal Syndrome	Subclavian Artery Stenosis Subclavian Steal Phenomenon Subclavian Steal Steno-Occlusive Disease Subclavian Steal
Nephrosclerosis	Renal Sclerosis
Shwartzman Phenomenon	Shwartzman Reaction
Eclampsia	Eclampsia In Puerperium Postpartum Eclampsia Eclampsia, Postpartum Puerperal Eclampsia
Hemarthrosis	Haemarthrosis Of Shoulder Joint Haemarthrosis Of The Ankle And Foot Haemarthrosis Of The Pelvic Region And Thigh Hemarthrosis Involving Ankle And Foot Hemarthrosis Involving Forearm Hemarthrosis Involving Hand Hemarthrosis Involving Lower Leg Hemarthrosis Involving Pelvic Region And Thigh Hemarthrosis Involving Shoulder Region Hemarthrosis Involving Upper Arm Hemarthrosis Of Ankle And/Or Foot Hemarthrosis Of Forearm Hemarthrosis Of Hand Hemarthrosis Of Lower Leg Hemarthrosis Of Shoulder Hemarthrosis Of Shoulder Region Hemarthrosis Of The Ankle And Foot Hemarthrosis Of The Ankle And/Or Foot Hemarthrosis Of The Forearm Hemarthrosis Of The Hand Hemarthrosis Of The Lower Leg Hemarthrosis Of The Pelvic Region And Thigh Hemarthrosis Of The Shoulder Region Hemarthrosis Of The Upper Arm Hemarthrosis Of Upper Arm
Lipoprotein Quantitative Trait Locus	Coronary Artery Disease Coronary Artery Anomaly Coronary Artery Disease, Susceptibility To Myocardial Ischemia Congenital Anomaly Of Coronary Artery Coronary Arteriosclerosis Coronary Disease Coronary Heart Disease Coronary Artery Disorder LPAQTL Lpa Deficiency, Congenital Coronary Artery Abnormality Coronary Artery Anomaly, Congenital Chd Coronary Syndrome Congenital Malformations Of Coronary Vessels Malformation Of Coronary Vessels Congenital Coronary Artery Anomaly Congenital Coronary Artery Deformity Congenital Coronary Artery Disorder Abnormal Coronary Artery Congenital Coronary Artery Malposition Congenital Coronary Disease Congenital Anomaly Of Coronary Arteries
High Molecular Weight Kininogen Deficiency	HMWK DEFICIENCY Fitzgerald Trait Congenital High-Molecular-Weight Kininogen Deficiency Flaujeac Factor Deficiency Kininogen Deficiency, High Molecular Weight Kininogen Deficiency Hmwk High-Molecular-Weight Kininogen Deficiency, Congenital
Active Peptic Ulcer Disease	Gi Bleeding Active Peptic Ulcer Gastrointestinal Hemorrhage
Synovial Angioma	Hemangioma Of Synovium Synovial Hemangioma
Toxic Shock Syndrome	Septic Shock Toxic Shock Tss Shock, Septic Staphylococcal Toxic Shock Syndrome Tss - [Toxic Shock Syndrome]
Peripheral Vascular Disease	Peripheral Arterial Disease Arterial Occlusive Disease Arterial Occlusive Diseases Pad Peripheral Vascular Diseases Peripheral Occlusive Disease Peripheral Arterial Diseases Helicobacter Infections
Hepatic Vascular Disease	Vascular Disorder Of Liver
Lemierre'S Syndrome	Lemierre Syndrome Lemierre Postanginal Sepsis Necrobacillosis Postanginal Sepsis Secondary To Orophyngeal Infection Septic Phlebitis Of The Internal Jugular Vein Fusobacterium Infections Acute Sore Throat Human Necrobacillosis Postanginal Sepsis Oropharyngeal Infection Leading To Secondary Septic Thrombophlebitis Of The Internal Jugular Vein
Atrial Fibrillation	A-Fib Fibrillation, Atrial Af - [Atrial Fibrillation] Rapid Atrial Fibrillation A Fib - [Atrial Fibrillation]
Endocardium Disease
Pericardium Disease
Pulmonary Hypertension	Primary Pulmonary Hypertension Hypertension Pulmonary Hypertension, Pulmonary Hypertension, Pulmonary, Primary Idiopathic Pulmonary Hypertension Idiopathic Pulmonary Arterial Hypertension Pulmonary Htn - [Hypertension]
Severe Acute Respiratory Syndrome	Sars Sars-Cov Infection Sars-1 Sar Deficiency Sars - [Severe Acute Respiratory Syndrome]
Vitamin K Deficiency Bleeding	Vitamin K Deficiency Deficiency Of Vitamin K Vitamin K Vitamin K Deficiency Hemorrhagic Disease
Cardiac Tamponade	Pericardial Tamponade Rose'S Tamponade
Primary Thrombocytopenia
Esophageal Varix	Esophageal Varices Bleeding Esophageal Varices Bleeding Oesophageal Varices Esophageal Varices In Disease Classified Elsewhere, With Bleeding Esophageal Varices With Bleeding Esophageal Varices With Bleeding In Disease Ec Esophageal Varices Without Bleeding Esophageal Varices Without Mention Of Bleeding
Cholangitis	Acute Cholangiolitis Ascending Cholangitis Cholangiolitis Cholangitis Nos Chronic Cholangiolitis Hepatic Duct Inflammation Acute Cholangitis Bile Duct Inflammation
Polycythemia	Erythrocythemia Polycythemia Vera Polycythaemia Due To High Altitude
Myocarditis	Myocardial Inflammation Inflammatory Cardiomyopathy
Hemangioma	Hemangiomas
Antithrombin Iii Deficiency	Hereditary Antithrombin Deficiency Congenital Antithrombin Iii Deficiency Hereditary Thrombophilia Due To Congenital Antithrombin Deficiency AT3D Thrombophilia Due To Antithrombin Iii Deficiency Thph7 Hereditary Thrombophilia Due To Congenital Antithrombin 3 Deficiency Thrombophilia 7 Due To Antithrombin Iii Deficiency At Iii Deficiency Congenital At-Iii Deficiency Inherited Antithrombin Deficiency Antithrombin 3 Deficiency Antithrombin Deficiency Antithrombin-Iii Deficiency At-Iii Deficiency Thrombophilia Due To Antithrombin-Iii Deficiency
Cardiovascular System Disease	Abnormality Of The Cardiovascular System Cardiovascular Disease Disease Of Subdivision Of Hemolymphoid System Disorder Of Cardiovascular System Cardiovascular Diseases
Epidural Abscess	Abscess Epidural
Infective Endocarditis	Bacterial Endocarditis Endocarditis, Infective Infectious Endocarditis Endocarditis Infective
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Emphysematous Cholecystitis	Gaseous Pericholecystitis
Aortic Aneurysm	Aortic Rupture Thoracoabdominal Aortic Aneurysm, Ruptured Ruptured Aortic Aneurysm Aortic Aneurysms Aortic Aneurysm Without Mention Of Rupture Nos Ruptured Abdominal Aortic Aneurysm Aortic Aneurysm, Ruptured Ruptured Thoracic Aortic Aneurysm
Intracranial Hypotension
Portal Vein Thrombosis	Phlebitis Of Portal Vein Deep Vein Thrombosis Of Portal Vein Portal Thrombosis Pvt - [Portal Vein Thrombosis] Portal Venous Thrombosis Portal Venous Embolism Portal Venous Obstruction Portal Venous Block Portal Vein Embolism Portal Vein Block Portal Obstruction Portal Embolism Portal Block Hepatic Portal Vein Obstruction Occlusion Of Hepatic Portal Vein Portal Vein Obstruction
Thrombophlebitis	Phlebitis And Thrombophlebitis Of Superficial Vessels Of Lower Extremities Superficial Thrombophlebitis Of Leg Thrombophlebitis Of A Superficial Leg Vein Thrombophlebitis Of Superficial Veins Of Lower Extremity
Bacterial Sepsis
Thrombasthenia
Polycythemia Vera	PV Polycythemia Rubra Vera Prv Osler-Vaquez Disease Chronic Erythremia Polycythaemia Rubra Vera Primary Polycythemia Vaquez Disease Polycythemia Vera, Somatic Osler-Vaquez Syndrome Proliferative Polycythaemia Polycythemia Ruba Vera Acquired Primary Erythrocytosis Heilmeyer-Schoner Disease Vaquez Osler Disease Primary Polycythaemia
Alpha-2-Plasmin Inhibitor Deficiency	Plasmin Inhibitor Deficiency Antiplasmin Deficiency Antiplasmin Defiency Anti-Plasmin Deficiency, Congenital Antiplasmin Deficiency, Congenital Congenital Alpha2-Antiplasmin Deficiency APLID Congenital Alpha2 Antiplasmin Deficiency
Speech And Communication Disorders	Language Disorder Communication Disorder Language Disorders Communication Disorders Speech Language Disorder Speech-Language Disorder Communication Impairment Speech And Language Disorder
Atherosclerosis Susceptibility	Atherosclerosis Atherosclerosis, Susceptibility To ATHS Atherogenic Lipoprotein Phenotype Alp Arteriosclerosis
Splenic Sequestration
Hepatic Infarction	Infarct Of Liver Hepatic Infarct Liver Infarct Liver Infarction
Von Willebrand Disease, Type 1	Von Willebrand Disease Type 1 VWD1 Von Willebrand'S Disease 1 Von Willebrand Disease Type I Von Willebrand Disease, Type I Vwd, Type 1 Vwd Type 1 Von Willebrand Disease 1 Von Willebrand Factor Deficiency Type 1 Von Willebrand Disease, Type 1, Susceptibility To
Ureteric Orifice Cancer	Malignant Neoplasm Of Ureteric Orifice Of Urinary Bladder Malignant Tumor Of Ureteric Orifice Orifice Of The Ureter
Hepatic Coma	Hepatic Encephalopathy Hepatocerebral Intoxication
Non-Severe Covid-19
Brachydactyly, Type D	Brachydactyly Type D BDD Stub Thumb Brachydactyly D
Splenic Abscess
Vertical Talus, Congenital	Congenital Vertical Talus CVT Congenital Convex Pes Valgus Rocker-Bottom Foot Deformity Vertical Talus Pes Valgus, Congenital Convex Congenital Convex Foot Congenital Rocker-Bottom Foot Rocker Bottom Foot Flatfoot Rocker-Bottom Foot Charcot-Marie-Tooth Disease, Foot Deformity Of
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Papilledema	Choked Disk Edema Of The Optic Disc
Blue Toe Syndrome
Coronavirus Infectious Disease
Carotid Artery Disease	Carotid Artery Diseases Disorder Of Carotid Artery
Leech Infestation	Hirudiniasis Leeches
Placental Abruption	Abruptio Placentae Abruptio Placenta Abortion, Threatened Threatened Miscarriage Haemorrhage Specified As Due To Threatened Abortion Spontaneous Threatened Abortion
Tricuspid Valve Disease	Rheumatic Tricuspid Valve Disease Disease Of Tricuspid Valve Rh. Tricuspid Valve Disease Rheumatic Disease Of Tricuspid Valve Tricuspid Disease Tricuspid Valve Disorder
Severe Covid-19
Intermediate Coronary Syndrome	Unstable Angina Angina At Rest Anginal Chest Pain At Rest Impending Infarction Preinfarction Angina Worsening Angina Angina, Unstable Myocardial Preinfarction Syndrome Angina Unstable Crescendo Angina Angina Decubitus Acute Coronary Insufficiency Unstable Angina Pectoris Preinfarctional Angina Pectoris Worsening Effort Angina Preinfarction Syndrome Unstable Angina Pectoris Syndrome Unstable Anginal Attack Unstable Cardiac Angina Unstable Chest Angina Unstable Heart Angina De Novo Effort Angina Pectoris Crescendo Angina Pectoris Ua - [Unstable Angina]
Anuria	Suppression Of Urinary Secretion
Autoimmune Disease Of Blood
Central Retinal Artery Occlusion
Occlusion Precerebral Artery	Occlusion And Stenosis Of Multiple And Bilateral Precerebral Arteries Occlusion And Stenosis Of Precerebral Artery
Angioedema, Hereditary, 3	Angioedema, Hereditary, Type Iii Hereditary Angioedema Type Iii Hereditary Angioedema Type 3 HAE3 Estrogen-Related Hae Estrogen-Sensitive Hae Angioneurotic Edema, Hereditary, With Normal C1 Inhibitor Concentration And Function Hae With Normal C1 Inhibitor Concentration And Function Hereditary Angioedema With Normal C1 Inhibitor Activity F12-Related Hereditary Angioedema With Normal C1inh F12-Related Hae With Normal C1 Inhibitor Hae 3 Hae-Iii Hereditary Angioneurotic Edema Type 3 Inherited Estrogen-Associated Angioedema Inherited Estrogen-Associated Angioneurotic Edema Inherited Estrogen-Dependent Angioedema Inherited Estrogen-Dependent Angioneurotic Edema Angioneurotic Edema Hereditary With Normal C1 Inhibitor Concentration And Function Hereditary Angioedema With Normal C1 Esterase Inhibitor Activity
Chronic Venous Insufficiency
Branch Retinal Artery Occlusion	Retinal Artery Occlusion Arterial Retinal Branch Occlusion Retinal Arterial Branch Occlusion
Pericardial Effusion	Noninflammatory Pericardial Effusion Pericardium Effusion
Ankylosing Spondylitis 1	Ankylosing Spondylitis, Susceptibility To, 1
Limb Ischemia
Critical Illness Polyneuropathy	Polyneuropathy, Critical Illness
Vertebral Artery Occlusion	Occlusion And Stenosis Of Vertebral Artery
Mediastinitis
Acalculous Cholecystitis	Acute Cholecystitis Without Calculus Acute Acalculous Cholecystitis Cholecystitis Without Calculus
Tricuspid Valve Insufficiency	Tricuspid Regurgitation Tricuspid Valve Regurgitation Tricuspid Incompetence Tr - [Tricuspid Regurgitation] Tricuspid Valve Incompetency Tricuspid Valve Annular Incompetency
Middle Cerebral Artery Infarction	Infarction, Middle Cerebral Artery Infarction Middle Cerebral Artery
Angiodysplasia	Angiodysplasia Of Colon Angiodysplasia Of Stomach And Duodenum With Hemorrhage Angiodysplasia Of Large Intestine Telangiectasia Of Colon Vascular Ectasia Of Colon Av - [Angiodysplasia Malformation Of Colon] Colon Angiodysplasia Colonic Angiodysplasia Vascular Ectasia Of Large Intestine
Mastoiditis	Mastoiditis Nec
Rocky Mountain Spotted Fever	Brazillian Spotted Choix Exanthematic Typhus Of Sao Paulo Fiebre Maculosa Fiebre Manchada Sao Paulo Typhus So Paulo Fever Tick Typhus Tobia Fever Rmsf Typhus, Tick
Cholesterol Embolism	Atheroembolism Trash Foot Cholesterol Crystal Embolism Purple Toe Syndrome Warfarin Blue Toe Syndrome Embolism, Cholesterol Cholesterol Embolus Syndrome
Mitral Valve Stenosis	Mitral Stenosis Rheumatic Mitral Stenosis Ms - [Mitral Stenosis] Mitral Valvular Stricture Mitral Valve Stricture Mitral Stricture Chronic Mitral Stenosis Mitral Obstruction Mitral Valve Obstruction Mitral Stenosis With Incompetence Mitral Stenosis With Regurgitation Rheumatic Mitral Insufficiency With Obstruction
Astrakhan Spotted Fever
Tricuspid Valve Stenosis	Tricuspid Stenosis Tricuspid Stricture Tricuspid Valve Stricture Tricuspid Insufficiency With Obstruction Tricuspid Insufficiency With Stenosis
Basilar Artery Occlusion
Acquired Thrombocytopenia	Secondary Thrombocytopenia
Viral Pneumonia	Pneumonia, Viral Acute Viral Pneumonia Bronchopneumonia Due To Viruses Other Than Influenza Viruses Interstitial Viral Pneumonia Viral Bronchopneumonia Viral Double Pneumonia Viral Lobar Pneumonia Viral Purulent Pneumonia Virus Interstitial Pneumonia Virus Lobar Pneumonia
Cecal Disease	Cecal Diseases Disorder Of Cecum
Mitral Valve Disease	Chronic Rheumatic Mitral Valve Rheumatic Mitral Insufficiency Disease Of Mitral Valve Mitral Rh Valve Dis. Rheumatic Disease Of Mitral Valve Rheumatic Mitral Valve Changes Rheumatic Mitral Valve Incompetence Rheumatic Mitral Valve Regurgitation Abnormality Of The Mitral Valve Diseases Of Mitral Valve Rheumatic Mitral Regurgitation
Livedoid Vasculitis	Livedoid Vasculopathy Livedo Reticularis With Summer Ulcerations Livedo Vasculitis Livedo Reticularis With Winter Ulcerations Segmental Hyalinizing Vasculopathy Milian Atrophie Blanche Segmental Hyalinizing Vasculitis Livedo Reticularis With Summer Ulceration
Aspiration Pneumonitis	Chemical Pneumonitis Mendelson'S Syndrome Aspiration Pneumonia Pneumonitis Due To Fumes And/Or Vapors Toxic Pneumonitis Mendelson'S Syndrome Resulting From A Procedure Mendelson Syndrome Resulting From A Procedure Pulmonary Acid Aspiration Syndrome Pneumonitis Due To Inhalation Of Gastric Secretions Mendelson Syndrome Due To Anaesthesia During Labour And Delivery Inhalation Of Stomach Contents Or Secretions, Nos Due To Anaesthesia During Labour And Delivery
Aspiration Pneumonia	Pneumonia, Aspiration Pneumonia Aspiration Aspiration Pneumonitis
Aortic Valve Insufficiency	Aortic Regurgitation Rheumatic Aortic Regurgitation Aortic Insufficiency Rheumatic Aortic Insufficiency Rheumatic Aortic Valve Insufficiency Aortic Incompetence Corrigan'S Disease Rheumatic Aortic Valve Regurgitation Aortic Valve Incompetency Ai - [Aortic Incompetence] Incompetent Aortic Valve Ar - [Aortic Regurgitation] Calcific Aortic Valve Regurgitation Myxomatous Aortic Valve Regurgitation Annular Incompetency Of Aortic Valve Austin Flint Murmur Flint Murmur Rheumatic Aortic Incompetence Rheumatic Ai - [Aortic Insufficiency]
Hypothyroidism	Thyroid Diseases Thyroid Disease Thyroid Deficiency Thyroid Insufficiency Dysfunction Thyroid Thyroid Dysfunction
Thrombocytopenic Purpura, Autoimmune	Idiopathic Thrombocytopenic Purpura Autoimmune Thrombocytopenic Purpura Immune Thrombocytopenic Purpura Itp Idiopathic Purpura AITP Ideopath Thrombocytopenic Pur Primary Thrombocytopenic Purpura Werlhof'S Disease Thrombocytopenic Purpura Autoimmune Purpura Thrombocytopenic Idiopathic Purpura, Thrombocytopenic, Idiopathic Autoimmune Thrombocytopenia Thrombocytopenia Due To Platelet Alloimmunization Idiopathic Thrombocytopenia Idiopathic Thrombocytopenia Purpura Frank'S Essential Thrombocytopenia Itp - [Idiopathic Thrombocytopenia Purpura] Werlhof Disease Primary Autoimmune Thrombocytopenic Purpura Haemorrhagic Purpura Essential Thrombocytopenia Purpura Haemorrhagica
Critical Covid-19
Heart Conduction Disease	Conduction Disorder Of The Heart Heart Rhythm Disease
Thrombocytopenia Due To Platelet Alloimmunization	Immune Thrombocytopenia Autoimmune Thrombocytopenia Immune Thrombocytopenic Purpura Itp Auto-Immune Thrombocytopenia Thrombocytopenia Due To Immune Destruction Autoimmune Thrombocytopenic Purpura Idiopathic Thrombocytopenic Purpura Werlhof Disease
Central Retinal Vein Occlusion	Crvo
Marburg Hemorrhagic Fever	Marburg Virus Disease Marburg Disease Green Monkey Disease Mhf Vervet Monkey Disease Mard - [Marburg Disease] Mvd - [Marburg Virus Disease] Marburg Haemorrhagic Fever Mhf - [Marburg Haemorrhagic Fever]
Volvulus Of Midgut	Volvulus Intestinal Volvulus Intestinal Malrotation, Familial Familial Intestinal Malrotation Twist Of Intestine, Bowel, Or Colon
Necrotizing Fasciitis	Fasciitis, Necrotizing
Transient Cerebral Ischemia	Transient Ischemic Attack Transient Ischemic Attacks Tia Tia - Transient Ischaemic Attack Transient Cerebral Ischaemia Ischemic Attack, Transient Intermittent Cerebral Ischemia Tia - [Transient Ischaemic Attack] Intermittent Cerebral Ischaemia Transient Cerebral Ischaemic Attack, Unspecified, Course Of Resolution Unspecified
Severe Pre-Eclampsia	Severe Preeclampsia Antepartum Severe Pre-Eclampsia Postpartum Severe Pre-Eclampsia Severe Pre-Eclampsia, With Delivery Severe Toxemia Severe Pre-Eclampsia, Antepartum Condition Or Complication Severe Pre-Eclampsia, Postpartum Condition Or Complication Severe Puerperal Pre-Eclampsia Severe Pre-Eclamptic Toxaemia Severe Pet - [Pre-Eclamptic Toxaemia]
Hypersplenism	Hypersplenia Big Spleen Syndrome Hyperfunction Of Spleen Increased Splenic Activity Spleen Metaplasia Splenic Metaplasia
Kidney Cortex Necrosis	Renal Cortical Necrosis
Nephrotic Syndrome	Finnish Congenital Nephrotic Syndrome Ns - [Nephrotic Syndrome] Nephrosis Syndrome Nephrosis Nos Glomerular Lesion Nephrosis
Medulloadrenal Hyperfunction
Acquired Polycythemia	Secondary Polycythemia Polycythemia, Secondary Secondary Erythrocytosis Polycythemia Secondary
Peptic Ulcer Disease	Peptic Ulcer Acute Peptic Ulcer With Hemorrhage Acute Peptic Ulcer With Hemorrhage And Perforation Acute Peptic Ulcer Without Hemorrhage And Without Perforation
Splenic Disease	Splenic Diseases Dyssplenism Spleen Disease Abnormality Of The Spleen Spleen Diseases
Pericoronitis	Operculitis
Mitral Valve Insufficiency	Mitral Regurgitation Congenital Insufficiency Of Mitral Valve Congenital Mitral Insufficiency Congenital Mitral Regurgitation Mitral Valve Incompetence Mitral Valve Regurgitation Mr - [Mitral Regurgitation] Mi - [Mitral Incompetence] Mitral Valve Annular Incompetency Congenital Mitral Valve Incompetence Congenital Mitral Valve Insufficiency Congenital Mitral Valve Regurgitation Congenital Mitral Incompetence
Dic In Newborn	Disseminated Intravascular Coagulation In Newborn
Ischemic Colitis	Colitis, Ischemic Irreversible Ischaemic Colitis
Exanthem	Exanthema Rash Rashes
Heart Aneurysm	Cardiac Aneurysm
Retinal Vascular Occlusion	Retinal Vasc. Occlusion Occlusion Of Retinal Vessels Retinal Obstruction
Patent Foramen Ovale	Atrial Septal Defect Within Oval Fossa Foramen Ovale Patent Ostium Secundum Atrial Septal Defect Atrial Septal Defect, Ostium Secundum Type Foramen Ovale, Patent Defect, Patent Or Persistent, Ostium Secundum Ostium Secundum Type Atrial Septal Defect Persistent Ostium Secundum Asd Ostium Secundum Type Ostium Secundum Asd Osasd Asd, Ostium Secundum Type Pfo - [Patent Foramen Ovale] Open Foramen Ovale Open Oval Foramen Persistent Foramen Ovale Secundum Atrial Septal Defect
Deficiency Anemia	Anemia Deficiency Anemias Anaemia
Cellulitis
Blood Protein Disease	Blood Protein Disorders Blood Protein Disorder
Coronary Aneurysm	Aneurysm Of Coronary Vessels Aneurysmal Lesion Of Coronary Artery Arteriovenous Aneurysm Of Coronary Vessels
Autoimmune Disease	Autoimmune Diseases Autoimmune Hypersensitivity Disease Hypersensitivity Reaction Type Ii Disease Type Ii Hypersensitivity Reaction Disease
Horner'S Syndrome	Horner Syndrome Bernard-Horner Syndrome Oculosympathetic Palsy Bernard Horner Syndrome Cervical Sympathetic Paralysis Von Passow Syndrome Cervical Sympathetic Dystrophy
Cavernous Hemangioma	Hemangioma, Cavernous Cavernoma Cavernous Haemangioma
Paralytic Ileus	Adynamic Ileus Paralytic Ileus Of Bowel Ileus Nos Paralysis Of Bowel Paralysis Of Intestine Adynamic Intestinal Obstruction Paralytic Intestinal Ileus
Hemorrhoid	Hemorrhoids Hemorrhoidal Disease Rectal Diseases Piles Unspecified Haemorrhoids Without Complication
Arteriovenous Malformation	Arteriovenous Malformations Arteriovenous Hemangioma Cirsoid Aneurysm Racemose Aneurysm Racemose Angioma Racemose Hemangioma Congenital Arteriovenous Malformation
Spotted Fever	Spotted Fevers Spotted Fever Group Rickettsial Disease Tick-Borne Rickettsioses Tick-Borne Typhus Nos Rocky Mountain Spotted Fever Sao Paulo Fever Sao Paulo Typhus Lone Star Spotted Fever Colombian Spotted Fever American Spotted Fever Tick Typhus Due To Rickettsia Rickettsii Rocky Mountain Tick Fever Boutonneuse Fever Mediterranean Tick Fever Fièvre Boutonneuse Mediterranean Spotted Fever Tick Typhus Due To Rickettsia Conorii African Tick Typhus Indian Tick Typhus Kenya Tick Typhus North Asian Tick Fever Siberian Tick Typhus Tick Typhus Due To Rickettsia Siberica North Asian Spotted Fever Queensland Tick Typhus Queensland Fever
Analbuminemia	ANALBA Congenital Analbuminemia Hypoalbuminemia
Coronary Artery Vasospasm	Coronary Vasospasm Coronary Artery Spasm
Vulvar Angiokeratoma	Fordyce Angiokeratoma Of Vulva Angiokeratoma Of Vulva
Kidney Papillary Necrosis	Necrotizing Renal Papillitis Papillary Necrosis Renal Papillitis Necrotizing
Dengue Hemorrhagic Fever	Severe Dengue Dengue Haemorrhagic Fever Dhf Severe Dengue Haemorrhagic Fever Severe Dengue Fever Dengue Shock Syndrome
Heart Valve Disease	Heart Valve Diseases Valvular Heart Disease Valvular Heart Diseases Heart Valve Prolapse
Atrial Heart Septal Defect	Atrial Septal Defect Atrial Septal Defects Atrioseptal Defect Auricular Septal Defect Congenital Atrial Septal Defect Interatrial Septal Defect Interauricular Septal Defect Heart Septal Defects, Atrial Septal Defect, Atrial
Cauda Equina Syndrome	Cauda Equina Polyradiculopathy
Bilirubin Metabolic Disorder	Hyperbilirubinemia Hereditary Hyperbilirubinemia Hyperbilirubinemia, Hereditary Hyperbilirubinaemia
Klebsiella Pneumonia	Pneumonia Due To Klebsiella Pneumoniae Klebsiella Infections Doid:13272 Klebsiella Lobar Pneumonia
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Aortic Dissection
Bernard-Soulier Syndrome	Giant Platelet Syndrome BSS Von Willebrand Factor Receptor Deficiency Bdplt1 Platelet Glycoprotein Ib Deficiency Bernard-Soulier Syndrome, Type A1 Bernard-Soulier Syndrome, Type B Bernard Soulier Syndrome Deficiency Of Platelet Glycoprotein 1b Hemorrhagiparous Thrombocytic Dystrophy Bernard-Soulier Syndrome Type C Bleeding Disorder, Platelet-Type, 1 Glycoprotein Ib, Platelet, Deficiency Of Giant Platelet Disorder, Isolated Giant Platelet Disease Macrothrombocytopenia, Familial Bernard-Soulier Type Bernard-Soulier Syndrome, Type C Bernard - Soulier Thrombopathy Hemorrhagic Dystrophic Thrombocytopenia Thrombopathy, Bernard-Soulier Platelet Glycoprotein 1b, Deficiency Of Hemorrhagioparous Thrombocytic Dystrophy Bernard-Soulier Syndrome Type A1 Bernard-Soulier Syndrome Type B Bleeding Disorder Platelet-Type 1 Gpd Macrothrombocytopenia, Familial, Bernard-Soulier Type
Renal Pelvis Squamous Cell Carcinoma	Epidermoid Carcinoma Of The Kidney Pelvis Squamous Cell Carcinoma Of Renal Pelvis
Gastric Hemangioma	Hemangioma Of Stomach
Respiratory Failure	Acute Respiratory Failure Chronic Respiratory Failure Respiratory Insufficiency Acute-On-Chronic Respiratory Failure Respiratory Disease Acute And Chronic Respiratory Failure Respiratory Insufficiency/Failure Chronic Respiratory Disease Pulmonary Valve Insufficiency Chronic Disease Of Respiratory System Respiration Disorders Respiratory Tract Diseases Lung Failure Nos Pulmonary Failure Arf - [Acute Respiratory Failure] Acute Respiratory Insufficiency Acute Pulmonary Insufficiency Acute Respiration Failure Chronic Respiration Failure
Extrinsic Cardiomyopathy
Pleural Disease	Pleural Diseases Disorder Of Pleura Non-Neoplastic Pleural Disease Pleural Disorders Non-Neoplastic Pleural Disorder
Type 2 Diabetes Mellitus	Insulin Resistance NIDDM Type 2 Diabetes Diabetes Mellitus, Non-Insulin-Dependent T2D Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Type Ii Maturity-Onset Diabetes Insulin Resistance, Severe, Digenic Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Noninsulin-Dependent, Association With Diabetes Mellitus, Noninsulin-Dependent, Late Onset Hypertension, Insulin Resistance-Related, Susceptibility To Insulin Resistance, Susceptibility To Non-Insulin-Dependent Diabetes Mellitus Type Ii Diabetes Mellitus Adult-Onset Diabetes Mellitus Maturity-Onset Diabetes Mellitus Diabetes Mellitus Type 2 Type Ii Diabetes Type 2 Diabetes Mellitus, Susceptibility To Diabetes, Type 2 Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 2, Susceptibility To Diabetes Mellitus, Noninsulin-Dependent, 2 Diabetes Mellitus, Type Ii, Susceptibility To Hypertension, Insulin Resistance-Related Adult-Onset Diabetes Aodm Diabetes Mellitus, Adult-Onset Diabetes Mellitus Type Ii Diabetes Mellitus Type 2, Susceptibility To Diabetes, Type Ii, Susceptibility To Diabetes Type 2 Diabetes Mellitus Adult Onset Diabetes Maturity Onset Diabetes Nonketotic Diabetes Non-Insulin Dependent Diabetes Mellitus T2dm - [Type 2 Diabetes Mellitus] Niddm - [Non Insulin Dependent Diabetes Mellitus] Dm2 Dm Type Ii Diabetic Type 2 Insulin Requiring Type 2 Diabetes Noninsulin Dependent Diabetes Non-Insulin-Dependent Diabetes Mellitus Without Complications Diabetes Due To Insulin Secretory Defect Diabetes Mellitus Due To Insulin Secretory Defect Non-Insulin-Dependent Diabetes Of The Young Senile Diabetes Nonketotic Hyperglycaemia Stable Diabetes
Hemolytic Uremic Syndrome, Atypical 1	Atypical Hemolytic-Uremic Syndrome Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 1 Atypical Hemolytic Uremic Syndrome Hemolytic Uremic Syndrome, Atypical, Susceptibility To Ahus AHUS1 Hemolytic-Uremic Syndrome Ahus 1 Ahus, Susceptibility To, 1 Hemolytic Uremic Syndrome, Atypical Non-Shiga-Like Toxin-Associated Hus Non-Stx-Hus Nonenteropathic Hus Atypical Hus Shiga Toxin-Associated Hemolytic Uremic Syndrome D+ Hus Ehec-Hus Hemolytic Uremic Syndrome Associated With Shiga Toxin-Producing Escherichia Coli Hemolytic Uremic Syndrome With Diarrhea Stec-Hus Shiga-Like Toxin-Associated Hus Stx-Hus Typical Hus Typical Hemolytic Uremic Syndrome Atypical Hemolytic Uremic Syndrome With Anti-Factor H Antibodies Atypical Hus With Anti-Factor H Antibodies Ahus With Anti-Factor H Antibodies Ahus With Neutralizing Autoantibodies Against Factor H Hemolytic Uremic Syndrome Atypical 1 Atypical Hemolytic Uremic Syndrome With H Factor Anomaly D Hus Hemolytic-Uremic Syndrome Without Diarrhea Hemolytic-Uremic Syndrome, Atypical, Type 1 Hemolytic Uremic Syndrome, Typical
Urinary Tract Infection	Urinary Tract Infections Uti Urinary Tract Infection Nos Uti - [Urinary Tract Infection] Uti Nos - [Urinary Tract Infection Nos] Urosepsis Nos E Coli Uti E Coli Urinary Tract Infection Escherichia Coli Uti
Hemophagocytic Lymphohistiocytosis	Lymphohistiocytosis, Hemophagocytic Haemophagocytic Syndrome Lymphohistiocytosis Hemophagocytic Hemophagocytic Syndrome Familial Hemophagocytic Lymphocytosis Histiocytoses Of Mononuclear Phagocytes Haemophagocytic Lymphohistiocytosis Nos
Sickle Cell Anemia	Hemoglobin Sc Disease Anemia, Sickle Cell Hbsc Disease Sickle Cell-Hemoglobin C Disease Syndrome Hb Ss Disease Sickle Cell Trait Drepanocytosis Haemoglobin Sc Disease Hb Sc Disease Hb-S/Hb-C Disease Hb-Ss Disease Without Crisis Hemoglobin S Disease Without Crisis Sickle Cell Anaemia Sickle-Cell/Hb-C Disease Without Crisis Sickle Cell - Hemoglobin C Disease Hbs Disease Hemoglobin S Disease Sickling Disorder Due To Hemoglobin S SKCA Sickle Cell Disease Sickle Cell-Hemoglobin C Disease Sickle-Cell Disease Carrier Sickle-Cell Heterozygous Disorder Haemoglobin A-S Genotype Hb-S - [Sickle Cell Haemoglobin] Carrier Sickle Cell Haemoglobin Trait As - [Sickle Cell Trait] Hbas - [Sickle Cell Haemoglobin Trait] Sickle-Cell Trait Haemoglobin Disease Haemoglobin Sickle Cell Trait Disorder Heterozygous Sickle Cell Trait Hbas - [Heterozygous Haemoglobin S]
Diabetes Mellitus	Diabetes
Acute Hemorrhagic Encephalitis
Heart Septal Defect	Septal Defect Heart Septal Defects Cardiac Septal Defects Congenital Septal Defect Of Heart
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Moyamoya Disease 1	Moyamoya Disease Spontaneous Occlusion Of The Circle Of Willis Mymy Progressive Intracranial Arterial Occlusion Moyamoya Syndrome MYMY1 Cerebrovascular Moyamoya Disease Moya-Moya Disease Progressive Intracranial Occlusive Arteropathy Idiopathic Moyamoya Disease
Intracranial Berry Aneurysm	Familial Aneurysmal Subarachnoid Hemorrhage Familial Berry Aneurysm Familial Intracranial Saccular Aneurysm Saccular Cerebral Aneurysm Aneurysm, Intracranial Berry Aneurysmal Subarachnoid Hemorrhage Aneurysm, Intracranial Berry, 1
Osteoporosis	Postmenopausal Osteoporosis Osteoporosis, Postmenopausal Bone Mineral Density Quantitative Trait Locus Bmnd Osteoporosis, Involutional Osteoporosis, Susceptibility To Osteoporosis, Postmenopausal, Susceptibility Bone Mineral Density Variation Qtl, Osteoporosis OSTEOP Involutional Osteoporosis Senile Osteoporosis Osteoporosis Postmenopausal Bone Mineral Density, Quantitative Trait Locus Osteoporosis, Senile Idiopathic Osteoporosis Bone Rarefaction Nos Type 1 Osteoporosis
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Heart Malformation Congenital Anomaly Of Heart Heart Defect Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Inguinal Hernia	Hernia Inguinal Hernia, Inguinal Inguinal Hernias Bubonocele Indirect Inguinal Hernia Direct Inguinal Hernia Oblique Inguinal Hernia Scrotal Hernia Ih - [Inguinal Hernia]
Aortic Aneurysm, Familial Abdominal, 1	Abdominal Aortic Aneurysm Aortic Aneurysm, Familial Abdominal 1 Aneurysm, Abdominal Aortic AAA Aortic Aneurysm, Abdominal AAA1 Aortic Aneurysm, Familial Abdominal Aortic Aneurysm Abdominal Abdominal Aortic Aneurysms Abdominal Aortic Aneurysm Without Mention Of Perforation Or Rupture Abdomen Aneurysm Abdominal Aorta Aneurysm Aneurysm Of Abdominal Aorta Aortic Abdomen Aneurysm Aaa - [Abdominal Aortic Aneurysm] Abdominal Aneurysm Abdominal Aorta Aneurysm Rupture Abdominal Aorta Aneurysm Ruptured Abdominal Aortic Aneurysm Which Has Ruptured Ruptured Aaa Abdomen Aorta Aneurysm Ruptured Abdomen Aorta Rupture Abdomen Aortic Aneurysm Rupture Abdomen Aneurysm Rupture Abdomen Aortic Aneurysm Ruptured Abdomen Aortic Rupture Abdominal Aorta Rupture Abdominal Aortic Rupture Rupture Abdomen Aorta Aneurysm Rupture Abdominal Aortic Aneurysm Ruptured Abdomen Aneurysm Ruptured Abdomen Aorta Ruptured Abdomen Aortic Ruptured Abdominal Aneurysm Ruptured Abdominal Aorta Ruptured Abdominal Aortic Ruptured Aorta Abdominalis Aneurysm False Abdomen Aorta Aneurysm Ruptured False Abdominal Aortic Aneurysm Ruptured False Abdominal Aorta Aneurysm Ruptured False Abdomen Aortic Aneurysm Ruptured
Patent Ductus Arteriosus 1	Patent Ductus Arteriosus PDA1 Pda Ductus Arteriosus, Patent Patent Ductus Arteriosus, Susceptibility To Patent Ductus Botalli Patency Of The Ductus Arteriosus Patent Ductus Arteriosus Familial Ductus Arteriosus Patent Patent Ductus Arteriosus - Persisting Type
Behcet Syndrome	Behcet Disease Behcet'S Syndrome Behcet'S Disease Behçet Disease Bd Adamantiades-Behcet Disease Triple Symptom Complex Behçet'S Disease Behet'S Syndrome Bd Syndrome Behçet Syndrome Behçet'S Syndrome Behcet Triple Symptom Complex Malignant Aphthosis Old Silk Route Disease Adamantiades-Behçet Disease
Migraine With Or Without Aura 1	Migraine Migraine With Or Without Aura, Susceptibility To, 1 Migraine Disorder Migraine Variant Migraines Migraine Disorders Mgr1 Mgau Ma Migraine With Or Without Aura Classic Migraine Common Migraine Disorder, Migraine Headache Migraine Headache Migrainous Migraine Headache Migraine Syndrome Headache Including Migraine Migraine, Susceptibility To
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-104010	Asciminib	Inhibitor	99.61%	Yes
HY-104010A	Asciminib hydrochloride	Inhibitor	99.79%	Yes

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-157229	STX-721	Inhibitor	98.25%	Phase 2
HY-B2203	Monocalcium glycerophosphate	Inhibitor	98.0%	Phase 2

Inhibitory Antibodies (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99271A	Tisotumab (powder)		/	Phase 3
HY-P991378	MORAb-066	Inhibitor	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (124)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-125845	(S,R,S)-AHPC		99.13%	Unkown
HY-18960	CHZ868	Inhibitor	98.69%	Unkown
HY-13491	GNF-5837	Inhibitor	99.44%	Unkown
HY-130709	PROTAC CDK2/9 Degrader-1	Degrader	99.85%	Unkown
HY-113437A	1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium		98.0%	Unkown
HY-11007	GNF-2	Inhibitor	99.82%	Unkown
HY-125834	GMB-475		98.69%	Unkown
HY-134877	BAY 2476568	Inhibitor	99.88%	Unkown
HY-N0600	Ginsenoside F3		99.84%	Unkown
HY-159147	SIAIS039		99.68%	Unkown
HY-131906	JAK2-IN-7		98.31%	Unkown
HY-E70134	Endo-β-N-acetylglucosaminidase F3		/	Unkown
HY-126619	Aspochalasin D		95.0%	Unkown
HY-162645	BPR5K230	Inhibitor	99.82%	Unkown
HY-164397	XMU-MP-5		99.00%	Unkown
HY-18952A	(Z)-SU5614		98.09%	Unkown
HY-133551	WF-47-JS03	Inhibitor	99.63%	Unkown
HY-110026	GTP-14564	Inhibitor	99.91%	Unkown
HY-12083	PPY-A	Inhibitor	98.02%	Unkown
HY-139997	DDC-01-163	Degrader	99.05%	Unkown
HY-16983	GNE-3500	Antagonist	98.90%	Unkown
HY-170820	XYD049	Inhibitor	99.46%	Unkown
HY-174981	LC-MF-4		98.05%	Unkown
HY-RS03482	CYP4F3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W1048555A	Mal-PEG2000-SCM		92.0%	Unkown
HY-W081348	1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one	Inhibitor	99.54%	Unkown
HY-107662	TCS PrP Inhibitor 13	Inducer	99.72%	Unkown
HY-113437	1,2-Dipalmitoyl-sn-glycerol 3-phosphate		/	Unkown
HY-151048	JBJ-07-149	Inhibitor	99.09%	Unkown
HY-162940	MerTK/Axl-IN-1	Inhibitor	/	Unkown
HY-170928	DA-0157	Inhibitor	99.59%	Unkown
HY-RS04112	E2F3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-113437AS	1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium		99.0%	Unkown
HY-N8448	3,4-Di-O-caffeoyl quinic acid methyl ester	Inhibitor	98.77%	Unkown
HY-RS19322	E2f3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W784556	5'-DMTr-dU(Allylamine-CO-F3)-3'-CE-phosphoramidite		/	Unkown
HY-110402	(S,R,S)-AHPC TFA		/	Unkown
HY-136526	BCR-ABL-IN-3	Inhibitor	/	Unkown
HY-101763B	(S,R,S)-AHPC dihydrochloride		/	Unkown
HY-112378	D-65476	Inhibitor	/	Unkown
HY-113777	22-HDHA		/	Unkown
HY-116597	L-783483	Agonist	/	Unkown
HY-121888	20-HEPE	Agonist	/	Unkown
HY-126920	AFG206		/	Unkown
HY-129764	Prostaglandin F3α	Substrate	/	Unkown
HY-129764A	(17E)-Prostaglandin F3α	Control	/	Unkown
HY-131244	ALK-IN-9	Inhibitor	/	Unkown
HY-142922	BCR-ABL-IN-4	Inhibitor	/	Unkown
HY-144451	TRK-IN-12	Inhibitor	/	Unkown
HY-146807	Type II TRK inhibitor 1	Inhibitor	/	Unkown
HY-147813	HIF-1α-IN-3	Inhibitor	/	Unkown
HY-149965	TRK-IN-23		/	Unkown
HY-154465	3’-F-3’-dG(iBu)-2’-phosphoramidite		/	Unkown
HY-155302	FLT3-IN-22	Inhibitor	/	Unkown
HY-156086	TRK-IN-24	Inhibitor	/	Unkown
HY-156102	c-ABL-IN-5		/	Unkown
HY-157432	EGFR-IN-97		/	Unkown
HY-158313	PROTAC EGFR degrader 13	Inhibitor	/	Unkown
HY-158465	GPEP FA2-KVANKT glycopeptide		/	Unkown
HY-161269	EGFR-IN-101	Inhibitor	/	Unkown
HY-162881	DS06652923	Inhibitor	/	Unkown
HY-163004	Type II TRK inhibitor 2	Inhibitor	/	Unkown
HY-163366	TRK-IN-28	Inhibitor	/	Unkown
HY-170497	EGFR-IN-140	Inhibitor	/	Unkown
HY-170852	QZ2135	Degrader	/	Unkown
HY-170927	JAK-IN-40		/	Unkown
HY-171884	BI-8128	Inhibitor	/	Unkown
HY-172478	DSPE-PEG1000-F3		/	Unkown
HY-172479	DSPE-PEG2000-F3		/	Unkown
HY-172479A	DSPE-PEG3400-F3		/	Unkown
HY-172480	DSPE-PEG5000-F3		/	Unkown
HY-174330	TRK-IN-31	Inhibitor	/	Unkown
HY-174330A	TRK-IN-31 hydrochloride	Inhibitor	/	Unkown
HY-174415	ZSH-2117		/	Unkown
HY-174437B	FLT3-IN-32 hydrochloride		/	Unkown
HY-174974	ISM7594	Inhibitor	/	Unkown
HY-175302	TRK-IN-32		/	Unkown
HY-175610	PROTAC FLT3/JAK2/BRD4 Degrader-1	Degrader	/	Unkown
HY-175864	EGFR-IN-173	Inhibitor	/	Unkown
HY-176259	F3-PEG8-RiboTAC		/	Unkown
HY-177030	RNase L ligand 3		/	Unkown
HY-178057	EGFR-IN-176		/	Unkown
HY-180172	TRK-IN-33		/	Unkown
HY-180967	PROTAC BCR-ABL Degrader-2		/	Unkown
HY-184598	CYB-5067		/	Unkown
HY-E70881	Endoglycosidase F3 (D165A mutant)		/	Unkown
HY-P10997	F3 peptide		/	Unkown
HY-R01574	hsa-miR-518f-3p mimic		/	Unkown
HY-R01574A	hsa-miR-518f-3p agomir		/	Unkown
HY-R01603	hsa-miR-520f-3p mimic		/	Unkown
HY-R01603A	hsa-miR-520f-3p agomir		/	Unkown
HY-R01683	hsa-miR-548f-3p mimic		/	Unkown
HY-R01683A	hsa-miR-548f-3p agomir		/	Unkown
HY-R03051	mmu-miR-344f-3p mimic		/	Unkown
HY-R03051A	mmu-miR-344f-3p agomir		/	Unkown
HY-R03176	mmu-miR-466f-3p mimic		/	Unkown
HY-R03176A	mmu-miR-466f-3p agomir		/	Unkown
HY-R03467	mmu-miR-669f-3p mimic		/	Unkown
HY-R03467A	mmu-miR-669f-3p agomir		/	Unkown
HY-RI01574	hsa-miR-518f-3p inhibitor		/	Unkown
HY-RI01574A	hsa-miR-518f-3p antagomir		/	Unkown
HY-RI01603	hsa-miR-520f-3p inhibitor		/	Unkown
HY-RI01603A	hsa-miR-520f-3p antagomir		/	Unkown
HY-RI01683	hsa-miR-548f-3p inhibitor		/	Unkown
HY-RI01683A	hsa-miR-548f-3p antagomir		/	Unkown
HY-RI03051	mmu-miR-344f-3p inhibitor		/	Unkown
HY-RI03051A	mmu-miR-344f-3p antagomir		/	Unkown
HY-RI03176	mmu-miR-466f-3p inhibitor		/	Unkown
HY-RI03176A	mmu-miR-466f-3p antagomir		/	Unkown
HY-RI03467	mmu-miR-669f-3p inhibitor		/	Unkown
HY-RI03467A	mmu-miR-669f-3p antagomir		/	Unkown
HY-RS02926	CNTN1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS04643	F3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS10899	POU2F3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS10902	POU3F3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS10906	POU4F3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS13207	SLC35F3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-116008	8-iso Prostaglandin F3α		/	Unkown
HY-154031	3'-F-3'-dA(Bz)-2'-Phosphoramidite		/	Unkown
HY-177031	RNA binder 3		/	Unkown
HY-RS16867	F3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23308	F3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23917	Cntn1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS25813	E2f3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Inhibitory Antibodies (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99271	Tisotumab		99.90%	Unkown
HY-P990222	Anti-Mouse/Rat IL-17A Antibody (17F3)	Inhibitor	99.41%	Unkown
HY-P990212	Anti-Mouse IL-6 Antibody (MP5-20F3)	Inhibitor	99.36%	Unkown
HY-P990145	Anti-Mouse VISTA Antibody (13F3)	Inhibitor	≥95.0%	Unkown
HY-P991451	Anti-ALPP Antibody	Inhibitor	95.34%	Unkown
HY-P992374	huDMB5F3	Inhibitor	/	Unkown
HY-P990411	Anti-F3/Factor III/Tissue Factor/CD142 Antibody	Inhibitor	98.88%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	F3	VGNC	VGNC:28687
Felis catus	F3	VGNC	VGNC:62026
Rattus norvegicus	F3	RGD	RGD:2587
Macaca mulatta	F3	VGNC	VGNC:106355
Canis familiaris	F3	VGNC	VGNC:54021
Mus musculus	F3	MGD	MGI:88381
Others	F3	NCBI