HPCAL4 - hippocalcin like 4 Gene

Also Known as HLP4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51440

Summary

The protein encoded by this gene is highly similar to human hippocalcin protein and hippocalcin like-1 protein. It also has similarity to rat neural visinin-like Ca2+-binding protein-type 1 and 2 proteins. This encoded protein may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. The transcript of this gene has multiple polyadenylation sites. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Biased expression in brain (RPKM 58.2), adrenal (RPKM 5.9) and 2 other tissues.

HPCAL4 Products (3)

mRNA Protein Name
NM_001282396.2 NP_001269325.1 hippocalcin-like protein 4 isoform 1
NM_001282397.2 NP_001269326.1 hippocalcin-like protein 4 isoform 2
NM_016257.4 NP_057341.1 hippocalcin-like protein 4 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HPCAL4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
HPCAL4 Q9UM19 ANKRD33 Homo sapiens Q7Z3H0-1
Y2H Array
32296183
Intra
HPCAL4 Q9UM19 ANKRD33 Homo sapiens Q7Z3H0-1
Y2H Prey Pooling
32296183
Intra
HPCAL4 Q9UM19 a0a1u9x8x8_human Homo sapiens A0A1U9X8X8
Y2H Array
32296183
Intra
HPCAL4 Q9UM19 a0a1u9x8x8_human Homo sapiens A0A1U9X8X8
Y2H Prey Pooling
32296183
Intra
HPCAL4 Q9UM19 MSRA Homo sapiens Q9UJ68
Y2H Array
32296183
Intra
HPCAL4 Q9UM19 MSRA Homo sapiens Q9UJ68
Y2H Prey Pooling
32296183
Intra
HPCAL4 Q9UM19 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra
HPCAL4 Q9UM19 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra
HPCAL4 Q9UM19 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Cross
HPCAL4 Q9UM19 tir Escherichia coli O157:H7 Q7DB77
Y2H
25519916
Cross
HPCAL4 Q9UM19 tir Escherichia coli O157:H7 Q7DB77
Lumier
25519916
Intra
HPCAL4 Q9UM19 DTX2 Homo sapiens Q86UW9
Y2H Prey Pooling
32296183
Intra
HPCAL4 Q9UM19 DTX2 Homo sapiens Q86UW9
Validated Y2H
25416956
Intra
HPCAL4 Q9UM19 DTX2 Homo sapiens Q86UW9
Y2H Pooling
16189514
Intra
HPCAL4 Q9UM19 DTX2 Homo sapiens Q86UW9
Y2H Array
25416956
Intra
HPCAL4 Q9UM19 DTX2 Homo sapiens Q86UW9
Y2H Array
32296183
Intra
HPCAL4 Q9UM19 FAM131C Homo sapiens Q96AQ9
Y2H Array
32296183
Intra
HPCAL4 Q9UM19 FAM131C Homo sapiens Q96AQ9
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06334 HPCAL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19260 Hpcal1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25749 Hpcal1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown